scGIR: deciphering cellular heterogeneity via gene ranking in single-cell weighted gene correlation networks

F Xu, H Hu, H Lin, J Lu, F Cheng, J Zhang… - Briefings in …, 2024 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for investigating
cellular heterogeneity through high-throughput analysis of individual cells. Nevertheless …

C-CSN: single-cell RNA sequencing data analysis by conditional cell-specific network

L Li, H Dai, Z Fang, L Chen - Genomics, Proteomics and …, 2021 - academic.oup.com
The rapid advancement of single-cell technologies has shed new light on the complex
mechanisms of cellular heterogeneity. However, compared to bulk RNA sequencing (RNA …

scVIC: Deep generative modeling of heterogeneity for scRNA-seq data

J Xiong, F Gong, L Ma, L Wan - Bioinformatics Advances, 2024 - academic.oup.com
Motivation Single-cell RNA sequencing (scRNA-seq) has become a valuable tool for
studying cellular heterogeneity. However, the analysis of scRNA-seq data is challenging …

[HTML][HTML] Leveraging gene correlations in single cell transcriptomic data

K Silkwood, E Dollinger, J Gervin, S Atwood, Q Nie… - BioRxiv, 2023 - ncbi.nlm.nih.gov
BACKGROUND: Many approaches have been developed to overcome technical noise in
single cell RNA-sequencing (scRNAseq). As researchers dig deeper into data—looking for …

scGENA: a single-cell gene coexpression network analysis framework for clustering cell types and revealing biological mechanisms

YA Algabri, L Li, ZP Liu - Bioengineering, 2022 - mdpi.com
Single-cell RNA-sequencing (scRNA-seq) is a recent high-throughput technique that can
measure gene expression, reveal cell heterogeneity, rare and complex cell populations, and …

Evaluating measures of association for single-cell transcriptomics

MA Skinnider, JW Squair, LJ Foster - Nature methods, 2019 - nature.com
Single-cell transcriptomics provides an opportunity to characterize cell-type-specific
transcriptional networks, intercellular signaling pathways and cellular diversity with …

A gene rank based approach for single cell similarity assessment and clustering

Y Xu, HD Li, Y Pan, F Luo, FX Wu… - IEEE/ACM transactions …, 2019 - ieeexplore.ieee.org
Single-cell RNA sequencing (scRNA-seq) technology provides quantitative gene expression
profiles at single-cell resolution. As a result, researchers have established new ways to …

scID: identification of transcriptionally equivalent cell populations across single cell RNA-seq data using discriminant analysis

K Boufea, S Seth, NN Batada - BioRxiv, 2018 - biorxiv.org
The power of single cell RNA sequencing (scRNA-seq) stems from its ability to uncover cell
type-dependent phenotypes, which rests on the accuracy of cell type identification. However …

scID uses discriminant analysis to identify transcriptionally equivalent cell types across single-cell RNA-seq data with batch effect

K Boufea, S Seth, NN Batada - IScience, 2020 - cell.com
The power of single-cell RNA sequencing (scRNA-seq) stems from its ability to uncover cell
type-dependent phenotypes, which rests on the accuracy of cell type identification. However …

[PDF][PDF] Liu, Z.-P. scGENA: A Single-Cell Gene Coexpression Network Analysis Framework for Clustering Cell Types and Revealing Biological Mechanisms …

YA Algabri, L Li - 2022 - academia.edu
Single-cell RNA-sequencing (scRNA-seq) is a recent high-throughput technique that can
measure gene expression, reveal cell heterogeneity, rare and complex cell populations, and …