Imaging the role of inflammation in mood and anxiety-related disorders

JC Felger - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

[HTML][HTML] Inflammation in fear-and anxiety-based disorders: PTSD, GAD, and beyond

V Michopoulos, A Powers, CF Gillespie… - …, 2017 - nature.com
The study of inflammation in fear-and anxiety-based disorders has gained interest as
growing literature indicates that pro-inflammatory markers can directly modulate affective …

Brain structures implicated in inflammation-associated depression

NA Harrison - Inflammation-associated depression: Evidence …, 2017 - Springer
Systemic inflammation rapidly impairs mood, motivation, and cognition inducing a
stereotyped cluster of symptoms collectively known as “sickness behaviors.” When …

Inflammation negatively correlates with amygdala-ventromedial prefrontal functional connectivity in association with anxiety in patients with depression: Preliminary …

ND Mehta, E Haroon, X Xu, BJ Woolwine, Z Li… - Brain, behavior, and …, 2018 - Elsevier
Biomarkers of inflammation, including inflammatory cytokines and the acute-phase reactant
C-reactive protein (CRP), are reliably increased in a subset of patients with depression …

[HTML][HTML] Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity

NA Harrison, L Brydon, C Walker, MA Gray… - Biological …, 2009 - Elsevier
BACKGROUND: Inflammatory cytokines are implicated in the pathophysiology of
depression. In rodents, systemically administered inflammatory cytokines induce depression …

[HTML][HTML] Inflammatory markers in substance use and mood disorders: a neuroimaging perspective

K Agarwal, P Manza, M Chapman, N Nawal… - Frontiers in …, 2022 - frontiersin.org
Chronic exposure to addictive drugs in substance use disorders and stressors in mood
disorders render the brain more vulnerable to inflammation. Inflammation in the brain, or …

Greater amygdala activity and dorsomedial prefrontal–amygdala coupling are associated with enhanced inflammatory responses to stress

KA Muscatell, K Dedovic, GM Slavich… - Brain, behavior, and …, 2015 - Elsevier
Psychological stress is implicated in the etiology of many common chronic diseases and
mental health disorders. Recent research suggests that inflammation may be a key …

Role of inflammation in the development of neuropsychiatric symptom domains: evidence and mechanisms

L Capuron, N Castanon - Inflammation-associated depression: Evidence …, 2017 - Springer
The finding that inflammatory markers are elevated in various neuropsychiatric disorders
raises the need of identifying the precise research domain criteria driven by inflammation …

[HTML][HTML] Inflammation-related functional and structural dysconnectivity as a pathway to psychopathology

DR Goldsmith, M Bekhbat, ND Mehta, JC Felger - Biological psychiatry, 2023 - Elsevier
Findings from numerous laboratories and across neuroimaging modalities have consistently
shown that exogenous administration of cytokines or inflammatory stimuli that induce …

[HTML][HTML] Therapeutic implications of brain–immune interactions: treatment in translation

AH Miller, E Haroon, JC Felger - Neuropsychopharmacology, 2017 - nature.com
A wealth of data has been amassed that details a complex, yet accessible, series of
pathways by which the immune system, notably inflammation, can influence the brain and …