[HTML][HTML] microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis

F Ahangari, NL Price, S Malik, M Chioccioli… - JCI insight, 2023 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease. Recent
findings have shown a marked metabolic reprogramming associated with changes in …

MicroRNA-34a promotes endothelial dysfunction and mitochondrial-mediated apoptosis in murine models of acute lung injury

D Shah, P Das, MA Alam, N Mahajan… - American journal of …, 2019 - atsjournals.org
Recent evidence has shown that microRNAs (miRs) are involved in endothelial dysfunction
and vascular injury in lung-related diseases. However, the potential role of miR-34a in the …

Integrated analyses identify the involvement of microRNA-26a in epithelial–mesenchymal transition during idiopathic pulmonary fibrosis

H Liang, Y Gu, T Li, Y Zhang, L Huangfu, M Hu… - Cell death & …, 2014 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and highly lethal
fibrotic lung disease with poor treatment and unknown etiology. Emerging evidence …

[HTML][HTML] miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways

L Ge, DM Habiel, PM Hansbro, RY Kim, SA Gharib… - JCI insight, 2016 - ncbi.nlm.nih.gov
Maladaptive epithelial repair from chronic injury is a common feature in fibrotic diseases,
which in turn activates a pathogenic fibroblast response that produces excessive matrix …

MicroRNA-29c regulates apoptosis sensitivity via modulation of the cell-surface death receptor, Fas, in lung fibroblasts

S Matsushima, J Ishiyama - American Journal of Physiology …, 2016 - journals.physiology.org
MicroRNAs play an important role in the development and progression of various diseases,
such as idiopathic pulmonary fibrosis (IPF). Although the accumulation of aberrant …

MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiation

H Cui, S Banerjee, N Xie, J Ge, RM Liu… - American journal of …, 2016 - atsjournals.org
Although microRNAs (miRs) have been well recognized to play an important role in the
pathogenesis of organ fibrosis, there is a lack of evidence as to whether miRs directly …

MicroRNA-29c prevents pulmonary fibrosis by regulating epithelial cell renewal and apoptosis

T Xie, J Liang, Y Geng, N Liu, A Kurkciyan… - American journal of …, 2017 - atsjournals.org
Successful repair and renewal of alveolar epithelial cells (AECs) are critical in prohibiting
the accumulation of myofibroblasts in pulmonary fibrogenesis. MicroRNAs (miRNAs) are …

miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions

H Cui, J Ge, N Xie, S Banerjee… - … of Physiology-Lung …, 2017 - journals.physiology.org
Idiopathic pulmonary fibrosis is a well-known age-related disease. However, much less
recognized has been the aging associated pathogenesis of this disorder. As we and others …

The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis

H Liang, C Xu, Z Pan, Y Zhang, Z Xu, Y Chen, T Li… - Molecular Therapy, 2014 - cell.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and high-lethality fibrotic lung
disease characterized by excessive fibroblast proliferation, extracellular matrix …

Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancements

C Jiang, Y Guo, H Yu, S Lu, L Meng - Allergy, Asthma & Clinical …, 2019 - Springer
Abstract MicroRNA-21 (miR-21), probably one of the most studied miRNAs to date, is found
pleiotropic in various biological events. Its emerging role in pulmonary remodeling has …