Reactive sulfur compounds in the fight against COVID-19

M Iciek, A Bilska-Wilkosz, M Kozdrowicki, M Górny - Antioxidants, 2022 - mdpi.com
The SARS-CoV-2 coronavirus pandemic outbreak in 2019 resulted in the need to search for
an effective and safe strategy for treating infected patients, relieving symptoms, and …

Use of thiols in the treatment of COVID-19: current evidence

M Cazzola, P Rogliani, SS Salvi, J Ora, MG Matera - Lung, 2021 - Springer
There is a possible role for oxidative stress, a state characterized by an altered balance
between the production of free radicals or reactive oxygen species (ROS) and antioxidant …

N-acetylcysteine and hydrogen sulfide in coronavirus disease 2019

AR Bourgonje, AK Offringa, LE van Eijk… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Hydrogen sulfide (H2S) is one of the three main gasotransmitters that are
endogenously produced in humans and are protective against oxidative stress. Recent …

The Antiviral Roles of Hydrogen Sulfide by Blocking the Interaction between SARS‐CoV‐2 and Its Potential Cell Surface Receptors

J Dai, X Teng, S Jin, Y Wu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
The ongoing coronavirus disease 2019 (COVID‐19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is posing a great threat to the global …

The reactive sulfur species concept: 15 years on

GI Giles, MJ Nasim, W Ali, C Jacob - Antioxidants, 2017 - mdpi.com
Fifteen years ago, in 2001, the concept of “Reactive Sulfur Species” or RSS was advocated
as a working hypothesis. Since then various organic as well as inorganic RSS have …

N‐Acetylcysteine and Other Sulfur‐Donors as a Preventative and Adjunct Therapy for COVID‐19

HN du Preez, C Aldous, HG Kruger… - Advances in …, 2022 - Wiley Online Library
The airway epithelial glycocalyx plays an important role in preventing severe acute
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …

[HTML][HTML] Antioxidants and COVID-19

S DE FLORA, R Balansky… - Journal of preventive …, 2021 - ncbi.nlm.nih.gov
Oxidative mechanisms are not only involved in chronic degenerative diseases but also in
infectious diseases, among which viral respiratory diseases. Antioxidants have the capability …

Anti‐inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID‐19 therapy

V Citi, A Martelli, V Brancaleone, S Brogi… - British journal of …, 2020 - Wiley Online Library
The COVID‐19 pandemic caused by SARS‐Cov‐2 demands rapid, safe and effective
therapeutic options. In the last decades, the endogenous gasotransmitter hydrogen sulfide …

Hydrogen sulfide: From a toxic gas to a potential therapy for COVID-19 and inflammatory disorders

M Kumar - Nitric Oxide, 2023 - Elsevier
COVID-19 has been shown to induce neuroinflammation and CNS manifestations. A swift
and efficient treatment strategy is urgently warranted for the management of COVID …

Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …