[HTML][HTML] Influenza Viruses: Targetting Conserved Viral Ha-Stem, Matrix and Nucleo-Proteins to Disarm a Resilient and Recurring Pandemic

BO Oladejo, CF Adeboboye - RNA Viruses Infection, 2022 - intechopen.com
Much to the current worldwide pandemic caused by the SARs-Cov-2 virus, common flu
caused by Influenza virus remain a long-standing mayhem to global health. Influenza …

Influenza virus infections: clinical update, molecular biology, and therapeutic options

G Franci, L Palomba, A Falanga, C Zannella… - The microbiology of …, 2016 - Elsevier
The viral family Orthomyxoviridae comprises five genera, but only two are of medical
relevance in humans, namely: influenza A and B viruses. Influenza A viruses are further …

Preparing for pandemics: RNA vaccines at the forefront

JH Erasmus, DH Fuller - Molecular Therapy, 2020 - cell.com
With coronavirus disease 2019 (COVID-19), it is now clear that the preparedness of the
healthcare system for the levels of morbidity and mortality that could occur with a serious …

Multivalent next generation influenza virus vaccines protect against seasonal and pre-pandemic viruses

N Uno, TM Ross - Scientific Reports, 2024 - nature.com
Each year, new influenza virus vaccine formulations are generated to keep up with
continuously circulating and mutating viral variants. A next-generation influenza virus …

Influenza viruses and coronaviruses: Knowns, unknowns, and common research challenges

O Terrier, M Si-Tahar, M Ducatez, C Chevalier… - PLoS …, 2021 - journals.plos.org
The development of safe and effective vaccines in a record time after the emergence of the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a remarkable …

Influenza infection and therapy: a systems approach

CV Forst - Future Virology, 2012 - Taylor & Francis
Seasonal flu affects 5–20% of the human population each year. Although mortality rates are
typically< 0.1% and the pandemic 2009 H1N1 influenza strain has been well contained by …

Influenza and related viruses: Epidemiology, pathogenesis, and therapeutics

K Asha, C Meseko, B Kumar - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Influenza is a highly contagious respiratory disease caused by influenza A, B, and C viruses
in humans and accounts for 30% of all respiratory viral infections. These viruses (influenza A …

Influenza virus: a master tactician in innate immune evasion and novel therapeutic interventions

ACY Hsu - Frontiers in Immunology, 2018 - frontiersin.org
Influenza is a contagion that has plagued mankind for many decades, and continues to pose
concerns every year, with millions of infections globally. The frequent mutations and …

Towards a universal influenza vaccine: different approaches for one goal

GA Sautto, GA Kirchenbaum, TM Ross - Virology journal, 2018 - Springer
Influenza virus infection is an ongoing health and economic burden causing epidemics with
pandemic potential, affecting 5–30% of the global population annually, and is responsible …

Development of universal influenza vaccines targeting conserved viral proteins

SD Jazayeri, CL Poh - Vaccines, 2019 - mdpi.com
Vaccination is still the most efficient way to prevent an infection with influenza viruses.
Nevertheless, existing commercial vaccines face serious limitations such as availability …