Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease
characterized by insulin deficiency due to pancreatic β-cell loss and leads to …

Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by loss of insulin
producing beta cells and reliance on exogenous insulin for survival. T1D is one of the most …

Type 1 diabetes mellitus (T1D) is an autoimmune disease encompassing the T-cell-
mediated destruction of pancreatic β cells and the production of autoantibodies against islet …

Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to
the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular …

Abstract Immune‐mediated (auto‐immune) Type 1 diabetes mellitus is not a homogenous
entity, but nonetheless has distinctive characteristics. In children, it may present with …

Background Type 2 diabetes mellitus consists of an array of dysfunctions characterized by
hyperglycemia and resulting from the combination of resistance to insulin action, inadequate …

Type 1 diabetes (T1D) is perceived as a chronic immune-mediated disease with a
subclinical prodromal period characterized by selective loss of insulin-producing β-cells in …

Anti-islet autoantibodies serve as key markers in immune-mediated type 1 diabetes (T1D)
and slowly progressive T1D (SPIDDM), also known as latent autoimmune diabetes in adults …

Context: Autoantibodies that are reactive to islet antigens are present at the time of
diagnosis in most patients with type 1 diabetes. Additionally, approximately 10% of …

Type 1A diabetes (T1D) results from autoimmunity targeted at a limited number of molecules
that are expressed in the pancreatic β cell. Putative novel autoantigen candidates were …