Arginine (L-arginine), is an amino acid involved in a number of biological processes,
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …

The vascular endothelium is a crucial regulator of vascular function and homeostasis. Nitric
oxide (NO) is an important paracrine substance released by the endothelium to regulate …

l-arginine is the substrate for endothelial nitric oxide synthase (eNOS), and the precursor for
the synthesis of nitric oxide (NO). This amino acid exerts a number of actions in the …

Abstract l-Arginine is the substrate of endothelial nitric oxide synthase and the main
precursor of nitric oxide in the vascular endothelium, thus its effects are mediated largely by …

Hypertension is a major healthcare problem afflicting nearly 50 million individuals in the
United States. Despite its strong causal association with cardiovascular disease …

There is abundant evidence that the endothelium plays a crucial role in the maintenance of
vascular tone and structure. One of the major endotheliumderived vasoactive mediators is …

SUMMARY 1 Nitric oxide (NO) plays a fundamental role in the vasculature because of its
diverse influence in vascular protection, including its well‐reported antiproliferative, anti …

L-Arginine (Arg) is the substrate for the synthesis of nitric oxide (NO), the endothelium-
derived relaxing factor essential for regulating vascular tone and hemodynamics. NO …

The vascular endothelium is acknowledged to play an important role in vascular physiology.
Attention has focused on endothelial production of nitric oxide as a key element in many of …

Abstract l-Arginine is a semi essential amino acid synthesised from glutamine, glutamate
and proline via the intestinal-renal axis in humans and most mammals. l-Arginine …