S Sundaram, AR Johnson, L Makowski - Journal of carcinogenesis, 2013 - ncbi.nlm.nih.gov
Historically, cancer research has focused on identifying mutations or amplification of genes within the tumor, which informed the development of targeted therapies against affected …
Obesity is a risk factor for at least 13 different types of cancer, many of which are hormonally driven, and is associated with increased cancer incidence and morbidity. Adult obesity rates …
BHL Harris, VM Macaulay, DA Harris… - Cancer and Metastasis …, 2022 - Springer
Obesity-related cancers account for 40% of the cancer cases observed in the USA and obesity is overtaking smoking as the most widespread modifiable risk factor for …
NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …
EE Calle, R Kaaks - Nature Reviews Cancer, 2004 - nature.com
The prevalence of obesity is rapidly increasing globally. Epidemiological studies have associated obesity with a range of cancer types, although the mechanisms by which obesity …
Obesity is associated with a range of health outcomes that are of clinical and public health significance, including cancer. Herein, we summarize epidemiologic and preclinical …
PFS Etet, L Vecchio, AHN Kamdje, PN Mimche… - Seminars in Cancer …, 2023 - Elsevier
Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term imbalance between energy intake and expenditure. Available epidemiological and clinical …
Obesity is associated with increased risk and poor prognosis of many types of cancers. Several obesity-related host factors involved in systemic metabolism can influence tumor …
Obesity is a risk factor for cancer development and is associated with poor prognosis in multiple tumor types. The positive energy balance linked with obesity induces a variety of …