Epigenetic dysregulation is being increasingly recognized as a hallmark of cancer. Post-
translational modifications of histones, in particular, are known to play important roles gene …

Global alterations in epigenetic landscape are now recognized as a hallmark of cancer.
Epigenetic mechanisms such as DNA methylation, histone modifications, nucleosome …

Alterations in modifications of histones have been linked to deregulated expression of many
genes with important roles in cancer development and progression. The effects of these …

Cancer is a disease of genome sequence alterations as well as epigenetic changes.
Epigenetics refers in part to the mechanisms by which histones affect various DNA-based …

Post-translational modification of histones provides an important regulatory platform for
processes such as gene expression, DNA replication and repair, chromosome condensation …

Oncogenesis is a multistep process mediated by a variety of factors including epigenetic
modifications. Global epigenetic post-translational modifications have been detected in …

Histone posttranslational modifications represent a versatile set of epigenetic marks
involved not only in dynamic cellular processes, such as transcription and DNA repair, but …

It is now widely recognized that epigenetic events are important mechanisms underlying
cancer development and progression. Epigenetic information in chromatin includes covalent …

Chromatin-related proteins have emerged as important players in the initiation and
maintenance of several types of cancer. In addition to the established role of histone …

Epigenetic regulations play a crucial role in the expression of various genes that are
important in the normal cell function. Any alteration in these epigenetic mechanisms can …