Lithium is one of the most effect mood-stabilizing drugs prescribed especially for bipolar
disorder. Lithium has wide range effects on different molecular factors and neural …

Background: The effectiveness of lithium salts in neuropsychiatric disorders such as bipolar
disorder, Alzheimer's disease, and treatment-resistant depression has been documented in …

The mood stabilizer lithium is used successfully in the treatment of bipolar affective disorder.
However, treatment compliance is frequently poor and sudden withdrawal from lithium …

Lithium has been used for over half a century for the treatment of bipolar disorder as the
archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in …

The use of lithium for the prevention of recurrences in mood disorders has a 55-year history.
Nowadays, lithium is universally accepted as the first-choice mood-stabilizer (MS) for …

Lithium is an effective drug for both the treatment and prophylaxis of bipolar disorder.
However, the precise mechanism of lithium action is not yet well understood. Extensive …

We studied the effect of lithium chloride on dopaminergic neurotransmission via D 2-like
receptors coupled to phospholipase A 2 (PLA 2). In unanesthetized rats injected iv with …

Lithium monotherapy has been proposed to have antidepressant and antimanic effects in
patients with bipolar disorder (BP). However, so far, it is lack of evidence to support this …

Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …

Since its discovery, lithium has been shown to act upon various neurotransmitter systems at
multiple levels of signaling in the brain. Lithium, affecting each neurotransmitter system …