Characterizing influences of DNA methylation (DNAm) on non-coding RNAs (ncRNAs) is
important to understand the mechanisms of gene regulation and cancer outcome. In our …

Background Disruption of DNA methylation (DNAm) is one of the key signatures of cancer,
however, detailed mechanisms that alter the DNA methylome in cancer remain to be …

Despite growing evidence demonstrates that the long non-coding ribonucleic acids
(lncRNAs) are critical modulators for cancers, the knowledge about the DNA methylation …

Long non-coding RNA (lncRNA) regulated by abnormal DNA methylation (ADM-lncRNA)
emerges as a biomarker for cancer diagnosis and treatment. This study comprehensively …

Different cancer types not only have common characteristics but also have their own
characteristics respectively. The mechanism of these specific and common characteristics is …

Despite growing appreciation of the importance of epigenetics in breast cancer, our
understanding of epigenetic alterations of non-coding RNAs (ncRNAs) in breast cancer …

The cancer epigenome exhibits global loss of DNA methylation, which contributes to
genomic instability and aberrant gene expression by mechanisms that are yet to be fully …

Aim: The goal of this study is to identify differentially methylated (DM) loci associated with
long noncoding RNA (lncRNA)/mRNA expression in non-small-cell lung cancer (NSCLC) …

The long noncoding RNAs (lncRNAs) are associated with tumorigenesis and progression of
cancer. While DNA methylation is a common epigenetic regulator of gene expression, the …

Colorectal cancer (CRC) is one of the leading causes of mortality worldwide. DNA
methylation is an important epigenetic modification for CRC. Although currently a number of …