[HTML][HTML] Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study …

HD Sesso, JAE Manson, AK Aragaki, PM Rist… - The American journal of …, 2022 - Elsevier
Background Cocoa extract is a source of flavanols that favorably influence vascular risk
factors in small and short-term trials, yet effects on clinical cardiovascular events are …

[HTML][HTML] Cocoa flavanol intake and biomarkers for cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials

X Lin, I Zhang, A Li, JAE Manson, HD Sesso… - The Journal of …, 2016 - Elsevier
Background: Cocoa flavanols may improve cardiometabolic health. Evidence from small
short-term randomized clinical trials (RCTs) remains inconsistent, and large long-term RCTs …

[HTML][HTML] Flavonoid-rich cocoa consumption affects multiple cardiovascular risk factors in a meta-analysis of short-term studies

MG Shrime, SR Bauer, AC McDonald… - The Journal of …, 2011 - Elsevier
A growing body of evidence suggests that the consumption of foods rich in polyphenolic
compounds, particularly cocoa, may have cardioprotective effects. No review, however, has …

[HTML][HTML] Effect of cocoa powder on the modulation of inflammatory biomarkers in patients at high risk of cardiovascular disease

M Monagas, N Khan, C Andres-Lacueva… - The American journal of …, 2009 - Elsevier
Background Epidemiologic studies have suggested that flavonoid intake plays a critical role
in the prevention of coronary heart disease. Because atherosclerosis is considered a low …

Cardioprotective effects of cocoa: Clinical evidence from randomized clinical intervention trials in humans

S Arranz, P Valderas‐Martinez… - Molecular Nutrition & …, 2013 - Wiley Online Library
Cocoa is an important source of polyphenols, which comprise 12–18% of its total dry weight.
The major phenolic compounds in cocoa and cocoa products are mainly flavonoids such as …

[HTML][HTML] Impact of cocoa flavanols on human health

MÁ Martin, S Ramos - Food and Chemical Toxicology, 2021 - Elsevier
Cocoa is a source of flavanols, and these phenolic compounds exert beneficial effects on
health and aging, and reduce the risk of suffering chronic diseases (cardiovascular …

[HTML][HTML] Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials

L Hooper, C Kay, A Abdelhamid, PA Kroon… - The American journal of …, 2012 - Elsevier
Background: There is substantial interest in chocolate and flavan-3-ols for the prevention of
cardiovascular disease (CVD). Objective: The objective was to systematically review the …

[HTML][HTML] Multivitamins in the prevention of cancer and cardiovascular disease: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized …

HD Sesso, PM Rist, AK Aragaki, S Rautiainen… - The American Journal of …, 2022 - Elsevier
Background Although older adults commonly take multivitamin-multimineral (MVM)
supplements to promote health, evidence on the use of daily MVMs on invasive cancer is …

[HTML][HTML] Short-term effect of cocoa product consumption on lipid profile: a meta-analysis of randomized controlled trials

L Jia, X Liu, YY Bai, SH Li, K Sun, C He… - The American journal of …, 2010 - Elsevier
Background: The effect of cocoa products on lipid changes is controversial. Objectives: We
aimed to identify and quantify the effect of cocoa on total cholesterol, LDL cholesterol, and …

Cocoa and cardiovascular health

R Corti, AJ Flammer, NK Hollenberg, TF Lüscher - Circulation, 2009 - Am Heart Assoc
Epidemiological data demonstrate that regular dietary intake of plant-derived foods and
beverages reduces the risk of coronary heart disease and stroke. Among many ingredients …