The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply
and the cerebral parenchyma, controlling the transport of material to and from the brain …

Major psychiatric disorders affect 25% of the population. While genetic and environmental
risk factors have been identified, the underlying pathophysiology of conditions, such as …

The mechanisms underlying the development and progression of psychiatric illnesses are
only partially known. Clinical data suggest blood‐brain barrier (BBB) breakdown and …

The blood–brain barrier (BBB) is the specialized system of brain microvascular endothelial
cells (BMVEC) that shields the brain from toxic substances in the blood, supplies brain …

Brain endothelial cells are unique among endothelial cells in that they express apical
junctional complexes, including tight junctions, which quite resemble epithelial tight …

The blood–brain barrier (BBB) is a diffusion barrier, which impedes influx of most
compounds from blood to brain. Three cellular elements of the brain microvasculature …

The blood brain barrier (BBB) is a highly dynamic interface between the central nervous
system (CNS) and periphery. The BBB is comprised of a number of components and is part …

Background: Despite decades of research, little clarity exists regarding pathogenic
mechanisms related to schizophrenia. Investigations on the disease biology of …

The use of psychostimulants and alcohol disrupts blood-brain barrier (BBB) integrity,
resulting in alterations to cellular function, and contributes to neurotoxicity. The BBB is the …

The adult quiescent blood–brain barrier (BBB), a structure organised by endothelial cells
through interactions with pericytes, astrocytes, neurons and microglia in the neurovascular …