[HTML][HTML] Improving the measurement of 25-hydroxyvitamin D

AM Wootton - Clinical Biochemist Reviews, 2005 - ncbi.nlm.nih.gov
Introduction 25-hydroxyvitamin D (25OHD) determination is of diagnostic importance for the
investigation of vitamin D deficiency and much more rarely, intoxication. Despite the name …

Laboratory reporting of 25-hydroxyvitamin D results: potential for clinical misinterpretation

N Binkley, MK Drezner, BW Hollis - Clinical chemistry, 2006 - academic.oup.com
Vitamin D deficiency is a common health problem, and healthcare providers frequently
measure circulating 25-hyroxyvitamin D concentration, the accepted standard for clinical …

25-hydroxy-Vitamin D status: limitations in comparison and clinical interpretation of serum-levels across different assay methods.

D Enko, L Fridrich, E Rezanka, R Stolba, J Ernst… - Clinical …, 2014 - europepmc.org
Background: Over the last decade, clinical interest to evaluate human 25-hydroxy-vitamin D
(25 [OH] D) serum levels has increased exponentially. In the present study, four …

Are clinical laboratories prepared for accurate testing of 25-hydroxy vitamin D?

RJ Singh - Clinical chemistry, 2008 - academic.oup.com
Vitamin D deficiency is an important concern, but assays for serum 25-hydroxy vitamin D (25-
OH-D), 1 the accepted marker for vitamin D nutritional status, are not standardized. A quick …

[HTML][HTML] Performance evaluation of four 25-hydroxyvitamin D assays to measure 25-hydroxyvitamin D2

J Freeman, K Wilson, R Spears, V Shalhoub… - Clinical biochemistry, 2015 - Elsevier
Objectives The ability of current immunoassays to accurately measure equimolar amounts of
25 (OH) D 2 and 25 (OH) D 3 has been recently questioned. This study determined serum …

Significance of serum 24, 25-dihydroxyvitamin D in the assessment of vitamin D status: a double-edged sword?

KD Cashman, A Hayes, K Galvin, J Merkel… - Clinical …, 2015 - academic.oup.com
Abstract BACKGROUND 24, 25-Dihydroxyvitamin D [24, 25 (OH) 2D] in serum may be both
a nuisance and nutritionally valuable. METHODS We investigated the impact of 24, 25 (OH) …

Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D

CT Sempos, AC Heijboer, DD Bikle… - British journal of …, 2018 - Wiley Online Library
The First International Conference on Controversies in Vitamin D was held in Pisa, Italy, 14–
16 June 2017. The meeting's purpose was to address controversies in vitamin D research …

25-hydroxyvitamin D: a difficult analyte

GD Carter - Clinical Chemistry, 2012 - academic.oup.com
In their article in the current issue of Clinical Chemistry, Farrell et al.(1) describe the latest in
a number of studies (2, 3) highlighting the method-related variability in serum 25 …

Measurement of 25-hydroxyvitamin D in the clinical laboratory: current procedures, performance characteristics and limitations

AM Wallace, S Gibson, A De La Hunty… - Steroids, 2010 - Elsevier
In this review we describe procedures, performance characteristics and limitations of
methods available for the measurement of 25-hydroxyvitamin (25OHD) since the year 2000 …

Current assays overestimate 25-hydroxyvitamin D3 and underestimate 25-hydroxyvitamin D2 compared with HPLC: need for assay-specific decision limits and …

P Glendenning, M Taranto, JM Noble… - Annals of clinical …, 2006 - journals.sagepub.com
Background: Clinical demand for quick, cheap, precise and accurate 25-hydroxyvitamin D
(25 (OH) D) results has led to the development of a variety of assay methods. Lack of …