Reconstruction of target genomes from sequence data produced by instruments that are
agnostic as to the species-of-origin may be confounded by contaminant DNA. Whether …

Motivation: For most research approaches, genome analyses are dependent on the
existence of a high quality genome reference assembly. However, the local accuracy of an …

Genome sequence assemblies provide the basis for our understanding of biology.
Generating error-free assemblies is therefore the ultimate, but sadly still unachieved goal of …

Generating the raw data for a de novo genome assembly project for a target eukaryotic
species is relatively easy. This democratization of access to large-scale data has allowed …

Limitations of genome sequencing techniques have led to dozens of assembly algorithms,
none of which is perfect. A number of methods for comparing assemblers have been …

The goal of many genome sequencing projects is to provide a complete representation of a
target genome (or genomes) as underpinning data for further analyses. However, it can be …

Background Genome assemblies are foundational for understanding the biology of a
species. They provide a physical framework for mapping additional sequences, thereby …

Data visualization plays an increasingly important role in NGS data analysis. With advances
in both sequencing and computational technologies, it has become a new bottleneck in …

As a part of the ELIXIR-EXCELERATE efforts in capacity building, we present here 10 steps
to facilitate researchers getting started in genome assembly and genome annotation. The …

Motivation The emergence of high-throughput sequencing technologies revolutionized
genomics in early 2000s. The next revolution came with the era of long-read sequencing …