An atlas of genetic influences on osteoporosis in humans and mice

JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan… - Nature …, 2019 - nature.com
Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral
density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative …

Genetics of osteoporosis from genome-wide association studies: advances and challenges

JB Richards, HF Zheng, TD Spector - Nature Reviews Genetics, 2012 - nature.com
Osteoporosis is among the most common and costly diseases and is increasing in
prevalence owing to the ageing of our global population. Clinically defined largely through …

Genetics of osteoporosis

M Peacock, CH Turner, MJ Econs… - Endocrine reviews, 2002 - academic.oup.com
Osteoporosis is a common multifactorial disorder of reduced bone mass. The disorder in its
most common form is generalized, affecting the elderly, both sexes, and all racial groups …

Genetics of osteoporosis

QY Huang, AWC Kung - Molecular Genetics and Metabolism, 2006 - Elsevier
Osteoporosis is a common disease with a strong genetic component. In recent years, some
progress has been made in understanding the genetic basis of osteoporosis. Genetic factors …

The genetics of bone mass and susceptibility to bone diseases

D Karasik, F Rivadeneira, ML Johnson - Nature Reviews Rheumatology, 2016 - nature.com
Osteoporosis is characterized by low bone mass and an increased risk of fracture. Genetic
factors, environmental factors and gene–environment interactions all contribute to a person's …

Genetic determinants of osteoporosis

SH Ralston - Current opinion in rheumatology, 2005 - journals.lww.com
Research has recently begun to clarify the genes and genetic variants that predispose to
osteoporosis and regulation of bone mass. Clinical applications of this research include the …

Genetics of osteoporosis

SH Ralston, AG Uitterlinden - Endocrine reviews, 2010 - academic.oup.com
Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass, defects in the microarchitecture of bone tissue, and an increased risk of …

Recent progress in understanding the genetic susceptibility to osteoporosis.

JM Zmuda, JA Cauley, RE Ferrell - Genetic epidemiology, 1999 - europepmc.org
Family and twin studies have established a genetic contribution to the etiology of
osteoporosis. The genes and allelic variants conferring osteoporotic risk are largely …

Role of genetics in osteoporosis

RR Recker, HW Deng - Endocrine, 2002 - Springer
Osteoporosis is a disease characterized by fragile bones and high susceptibility to low-
trauma fractures. It is a serious health problem, especially in elderly women. Bone mineral …

Genetic control of susceptibility to osteoporosis

SH Ralston - The Journal of Clinical Endocrinology & …, 2002 - academic.oup.com
Osteoporosis is a common disease with a strong genetic component. Twin studies have
shown that genetic factors play an important role in regulating bone mineral density (BMD) …