Q Lou, SC Janga, L Jiang - … of the ACM International Conference on …, 2020 - dl.acm.org
Nanopore genome sequencing is the key to enabling personalized medicine, global food security, and virus surveillance. The state-of-the-art base-callers adopt deep neural …
Motivation Nanopore sequencing is emerging as a key pillar in the genomic technology landscape but computational constraints limiting its scalability remain to be overcome. The …
Sequencing by translocating DNA fragments through an array of nanopores is a rapidly maturing technology that offers faster and cheaper sequencing than other approaches …
Nanopore sequencing generates noisy electrical signals that need to be converted into a standard string of DNA nucleotide bases using a computational step called basecalling. The …
Nanopore-based sequencers generate a series of raw electrical signal measurements that represent the contents of a biological sequence molecule passing through the sequencer's …
Background Nanopore-based DNA sequencing relies on basecalling the electric current signal. Basecalling requires neural networks to achieve competitive accuracies. To improve …
Genomics can transform health-care through precision medicine. Plummeting sequencing costs would soon make genome testing affordable to the masses. Compute efficiency …
Nanopore sequencers generate electrical raw signals in real-time while sequencing long genomic strands. These raw signals can be analyzed as they are generated, providing an …
Precision Medicine will rely on frequent genomic analysis, especially for patients undergoing cancer treatments or suffering from rare diseases. Sequence alignment is …