Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy,
with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is …

Preeclampsia (PE) is a complex, hypertensive disorder of pregnancy, demonstrating
considerable variability in maternal symptoms and fetal outcomes. Unfortunately, prior …

Background Preeclampsia (PE) is a life-threatening hypertensive pathology of pregnancy
affecting 3–5% of all pregnancies. To date, PE has no cure, early detection markers, or …

Background Preeclampsia is a life-threatening disorder of pregnancy, demonstrating a high
degree of heterogeneity in clinical features such as presentation, disease severity, and …

Preeclampsia is a potentially fatal pregnancy disorder affecting millions of women around
the globe. Dysregulation in gene and protein expression within key biological pathways …

Pre-eclampsia (PE) is a serious multi-factorial disorder of human pregnancy. It is associated
with changes in the expression of placental genes. Recent transcription profiling of placental …

Preeclampsia (PE) impacts 8 million mother–infant pairs worldwide each year. This human
pregnancy-specific disease characterized by hypertension and proteinuria accounts for …

Although it has been well documented that pre-eclampsia is caused by a combination of
maternal and fetal susceptibility genes, little is known about the precise etiology of this …

Preeclampsia has a familial component suggesting that one or more common alleles may
act as susceptibility genes. Some families may have” private” predisposing mutations. The …

Pre-eclampsia is a serious complication of pregnancy that can affect both maternal and fetal
outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is …