[HTML][HTML] Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer

J Zhu, H Teng, X Zhu, J Yuan, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Krüppel-like factor 3 (KLF3) is a key transcriptional repressor, which is involved
in various biological functions such as lipogenesis, erythropoiesis, and B cell development …

Comprehensive analysis of KLF family reveals KLF6 as a promising prognostic and immune biomarker in pancreatic ductal adenocarcinoma

J Lin, P Liu, K Sun, L Jiang, Y Liu, Y Huang, J Liu… - Cancer Cell …, 2024 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest tumors
worldwide, with extremely aggressive and complicated biology. Krüppel-like factors (KLFs) …

Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma cells

Q Wang, R Peng, B Wang, J Wang, W Yu… - Cancer …, 2018 - content.iospress.com
BACKGROUND: Krüppel-like factor 13 (KLF13), a member of the KLF family, is involved in
the development of immunological diseases and tumor progression. However, the …

Krüppel-like factor 8 is a potential prognostic factor for pancreatic cancer

Y Wei, G Chen, L You, Y Zhao - Chinese Medical Journal, 2014 - journals.lww.com
Background Pancreatic cancer is a lethal disease that is often diagnosed at an advanced
stage. There is a lack of information to predict the prognosis of pancreatic cancer. Krüppel …

[HTML][HTML] Expression of KLF9 in pancreatic cancer and its effects on the invasion, migration, apoptosis, cell cycle distribution, and proliferation of pancreatic cancer cell …

Z Zhong, F Zhou, D Wang, M Wu… - Oncology …, 2018 - spandidos-publications.com
Abstract Kruppel-like factor 9 (KLF9), a transcription factor, is critical for the inhibition of
growth and development of tumors, whereas its effects in pancreatic cancer remains …

Krüppel-like factor 6 suppresses the progression of pancreatic cancer by upregulating activating transcription factor 3

Q Xiong, Z Zhang, Y Yang, Y Xu, Y Zhou… - Journal of Clinical …, 2022 - mdpi.com
Background: As a member of the Krüppel-like factor (KLFs) family, Krüppel-like factor 6
(KLF6) plays a critical role in regulating key cellular functions. Presently, scholars have …

[HTML][HTML] KLF16 promotes proliferation in gastric cancer cells via regulating p21 and CDK4

P Ma, CQ Sun, YF Wang, YT Pan… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Krüppel-like factors (KLFs), such as KLF4, KLF2, KLF5 and KLF15, have been extensively
investigated in multi-cancers. However, KLF16, a member of KLFs, hasn't been well …

KLF2 is a clinical diagnostic and treatment biomarker of breast cancer

YZ Li, J Xie, RQ Wang, XQ Gao, PJ Liu… - Frontiers in Cell and …, 2023 - frontiersin.org
Background: As a highly prevalent malignancy among women worldwide, breast cancer,
remains a critical public health issue necessitating the development of novel therapeutics …

KLF4α up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer

D Wei, L Wang, M Kanai, Z Jia, X Le, Q Li, H Wang… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Krüppel-like factor 4 (KLF4) is a transcription factor associated with
tumor suppression and oncogenesis. KLF4 suppresses pancreatic tumorigenesis by …

KLF15 inhibits cell proliferation in gastric cancer cells via up-regulating CDKN1A/p21 and CDKN1C/p57 expression

C Sun, P Ma, Y Wang, W Liu, Q Chen, Y Pan… - Digestive Diseases and …, 2017 - Springer
Background Krüppel-like factors (KLFs) have been identified in multi-cancers and act as
oncogenes or tumor suppressors. The function of KLF15, one member of KLFs, has not been …