Until the year 1500 CE, Brazil was inhabited only by Native Americans belonging to different
linguistic groups, distributed along the coast and hinterland of the country. This scenario …

The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

The CCR5 is a chemokine receptor widely expressed by several immune cells that are
engaged in inflammatory responses. Some populations have individuals exhibiting a 32 bp …

The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The
effect of the CCR5* D32 allele in susceptibility to HIV infection and AIDS disease is well …

The expression of CCR5 gene, located on the short arm of chromosome three (3p21. 31),
leads to the formation of a protein that acts as a receptor for several chemokines. 1 A …

Entry of human immunodeficiency type 1 virus (HIV-1) into target cells requires both CD4and
one of the chemokine receptors. Viruses predominantly use one, or occasionally both, of the …

Although a potential involvement of the CCR5Δ32 variant has already been suggested in
relation to susceptibility to hepatitis C virus (HCV) infection, data from the literature is still …

Since around 1723, on the occasion of its initial colonization by Europeans, Rondonia has
received successive waves of immigrants. This has been further swelled by individuals from …

This study reports the frequencies of the CCR5D32 mutation of the beta-chemokine 5 gene
and discusses the possible effects of past and recent gene flow in three quilombo remnants …

2 (CCR2) that initially focused on their role in HIV-1 infection is expanding to other
inflammatory or immunological disorders. 1 The first genetic marker associated with …