Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

COVID‐19 is a life‐threatening disease leading to bilateral pneumonia and respiratory
failure. The underlying reasons why a smaller percentage of patients present with severe …

The recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
virus, the cause of coronavirus disease (COVID-19) and the associated ongoing pandemic …

In 2019–2020 a new coronavirus named SARS-CoV-2 was identified as the causative agent
of a several acute respiratory infection named COVID-19, which is causing a worldwide …

SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus-2) is the third coronavirus to
emerge as a cause of severe and frequently fatal pneumonia epidemics in humans, joining …

Background Immune dysregulation is a major factor in the development of severe
coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 …

Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

Background Chemokine levels in severe coronavirus disease 2019 (COVID-19) patients
have been shown to be markedly elevated. But the role of chemokines in mild COVID-19 …

The exact pathophysiology of severe COVID-19 is not entirely elucidated, but it has been
established that hyperinflammatory responses and cytokine storms play important roles. The …

The chemokine receptor CCR5 has been implicated in COVID-19. CCR5 and its ligands are
overexpressed in patients. The pharmacological targeting of CCR5 would improve the …