Imaging modalities for measuring body composition in patients with cancer: opportunities and challenges

UA Shah, TJ Ballinger, R Bhandari… - JNCI …, 2023 - academic.oup.com
Body composition assessment (ie, the measurement of muscle and adiposity) impacts
several cancer-related outcomes including treatment-related toxicities, treatment responses …

A critical evaluation of body composition modalities used to assess adipose and skeletal muscle tissue in cancer

KM Di Sebastiano, M Mourtzakis - Applied Physiology, Nutrition …, 2012 - cdnsciencepub.com
The majority of cancer patients experience some form of body composition change during
the disease trajectory. For example, breast cancer patients undergoing chemotherapy and …

The evolution of body composition in oncology—epidemiology, clinical trials, and the future of patient care: facts and numbers

JC Brown, EM Cespedes Feliciano… - Journal of cachexia …, 2018 - Wiley Online Library
There is growing interest from the oncology community to understand how body composition
measures can be used to improve the delivery of clinical care for the 18.1 million individuals …

Imaging body composition in cancer patients: visceral obesity, sarcopenia and sarcopenic obesity may impact on clinical outcome

C Yip, C Dinkel, A Mahajan, M Siddique, GJR Cook… - Insights into …, 2015 - Springer
In recent years, there has been increasing interest in the influence of body composition on
oncological patient outcomes. Visceral obesity, sarcopenia and sarcopenic obesity have …

Assessing dynamic change in muscle during treatment of patients with cancer: precision testing standards

L Arribas, A Sabaté-Llobera, MC Domingo, M Taberna… - Clinical Nutrition, 2022 - Elsevier
Background Computed tomography images acquired during routine cancer care provide an
opportunity to determine body composition with accuracy and precision. Quantification of …

A window beneath the skin: how computed tomography assessment of body composition can assist in the identification of hidden wasting conditions in oncology that …

LE Daly, CM Prado, AM Ryan - Proceedings of the Nutrition Society, 2018 - cambridge.org
Advancements in image-based technologies and body composition research over the past
decade has led to increased understanding of the importance of muscle abnormalities, such …

A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care

M Mourtzakis, CMM Prado, JR Lieffers… - Applied Physiology …, 2008 - cdnsciencepub.com
Human body composition is important in numerous cancer research domains. Our objective
was to evaluate clinically accessible methods to achieve practical and precise measures of …

Evaluation of automated computed tomography segmentation to assess body composition and mortality associations in cancer patients

EM Cespedes Feliciano, K Popuri… - Journal of cachexia …, 2020 - Wiley Online Library
Background Body composition from computed tomography (CT) scans is associated with
cancer outcomes including surgical complications, chemotoxicity, and survival. Most studies …

Importance of lean body mass in the oncologic patient

S Tsai - Nutrition in Clinical Practice, 2012 - Wiley Online Library
Loss of lean body develops from an imbalance in protein synthesis and catabolism and is
associated with a variety of different disease and nondisease states, including severe …

Body composition in pediatric solid tumors: state of the science and future directions

L Joffe, KL Schadler, W Shen, EJ Ladas - JNCI Monographs, 2019 - academic.oup.com
Sarcopenia (severe skeletal muscle wasting) and sarcopenic obesity (skeletal muscle
wasting in the setting of excess fat) have been increasingly recognized as important …