Trial of the route of early nutritional support in critically ill adults

SE Harvey, F Parrott, DA Harrison… - … England Journal of …, 2014 - Mass Medical Soc
Background Uncertainty exists about the most effective route for delivery of early nutritional
support in critically ill adults. We hypothesized that delivery through the parenteral route is …

A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral …

SE Harvey, F Parrott, DA Harrison… - Health Technology …, 2016 - discovery.ucl.ac.uk
BACKGROUND: Malnutrition is a common problem in critically ill patients in UK NHS critical
care units. Early nutritional support is therefore recommended to address deficiencies in …

Early use of supplemental parenteral nutrition in critically ill patients: results of an international multicenter observational study

J Kutsogiannis, C Alberda, L Gramlich… - Critical care …, 2011 - journals.lww.com
Objective: To evaluate the effect of using supplemental parenteral nutrition compared to
early enteral nutrition alone on nutritional and clinical outcomes. Design: A multicenter …

Early versus late parenteral nutrition in critically ill adults

MP Casaer, D Mesotten, G Hermans… - … England Journal of …, 2011 - Mass Medical Soc
Background Controversy exists about the timing of the initiation of parenteral nutrition in
critically ill adults in whom caloric targets cannot be met by enteral nutrition alone. Methods …

When early enteral feeding is not possible in critically ill patients: results of a multicenter observational study

NE Cahill, L Murch, K Jeejeebhoy… - Journal of Parenteral …, 2011 - Wiley Online Library
Background: Early enteral nutrition (EN) is the preferred strategy for feeding the critically ill;
however, it is not always possible to initiate EN within the recommended 24 to 48 hours …

A metaanalysis of treatment outcomes of early enteral versus early parenteral nutrition in hospitalized patients

JV Peter, JL Moran, J Phillips-Hughes - Critical care medicine, 2005 - journals.lww.com
Objective: Nutritional support as enteral or parenteral nutrition (PN) is used in hospitalized
patients to reduce catabolism. This study compares outcomes of early enteral nutrition (EN) …

Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a randomized controlled trial

GS Doig, F Simpson, EA Sweetman, SR Finfer… - Jama, 2013 - jamanetwork.com
Importance Systematic reviews suggest adult patients in intensive care units (ICUs) with
relative contraindications to early enteral nutrition (EN) may benefit from parenteral nutrition …

Outcomes in critically ill patients before and after the implementation of an evidence-based nutritional management protocol

J Barr, M Hecht, KE Flavin, A Khorana, MK Gould - Chest, 2004 - Elsevier
Objective To determine whether the implementation of a nutritional management protocol in
the ICU leads to the increased use of enteral nutrition, earlier feeding, and improved clinical …

Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle

F Simpson, GS Doig - Intensive care medicine, 2005 - Springer
Objective Controversy surrounds the use of parenteral nutrition in critical illness. Previous
overviews used composite scales to identify high-quality trials, which may mask important …

Impact of early parenteral nutrition completing enteral nutrition in adult critically ill patients (EPaNIC trial): a study protocol and statistical analysis plan for a …

MP Casaer, G Hermans, A Wilmer, G Van den Berghe - Trials, 2011 - Springer
Background For critically ill patients treated in intensive care units (ICU), two feeding
strategies are currently being advocated, one by American/Canadian and the other by …