Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination

J Tang, C Zeng, TM Cox, C Li, YM Son, IS Cheon… - Science …, 2022 - science.org
SARS-CoV-2 mRNA vaccination induces robust humoral and cellular immunity in the
circulation; however, it is currently unknown whether it elicits effective immune responses in …

Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

D Lapuente, J Fuchs, J Willar, A Vieira Antão… - Nature …, 2021 - nature.com
Several effective SARS-CoV-2 vaccines are currently in use, but effective boosters are
needed to maintain or increase immunity due to waning responses and the emergence of …

[HTML][HTML] The mucosal and serological immune responses to the novel coronavirus (SARS-CoV-2) vaccines

RWY Chan, S Liu, JY Cheung, JGS Tsun… - Frontiers in …, 2021 - frontiersin.org
Background Although the serological antibody responses induced by SARS-CoV-2 vaccines
are well characterized, little is known about their ability to elicit mucosal immunity. Objectives …

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

B Ying, B Whitener, LA VanBlargan… - Science translational …, 2021 - science.org
Although mRNA vaccines encoding the spike protein of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) prevent COVID-19, the emergence of new viral variants …

[PDF][PDF] SARS-CoV-2 mRNA vaccine induces robust specific and cross-reactive IgG and unequal neutralizing antibodies in naive and previously infected people

TM Narowski, K Raphel, LE Adams, J Huang, NA Vielot… - Cell reports, 2022 - cell.com
Understanding vaccine-mediated protection against severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) is critical to overcoming the global coronavirus disease 2019 …

[PDF][PDF] Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals

D Lozano-Ojalvo, C Camara, E Lopez-Granados… - Cell reports, 2021 - cell.com
The rapid development of mRNA-based vaccines against the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated vaccination …

Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

JP Evans, C Zeng, C Carlin, G Lozanski… - Science Translational …, 2022 - science.org
The waning efficacy of SARS-CoV-2 vaccines, combined with the continued emergence of
variants resistant to vaccine-induced immunity, has reignited debate over the need for …

Immune response in moderate to critical breakthrough COVID-19 infection after mRNA vaccination

K Paniskaki, M Anft, TL Meister… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 variants of concern (VOCs) can trigger severe endemic waves and vaccine
breakthrough infections (VBI). We analyzed the cellular and humoral immune response in 8 …

Distinct SARS-CoV-2 antibody reactivity patterns elicited by natural infection and mRNA vaccination

R Assis, A Jain, R Nakajima, A Jasinskas, S Khan… - npj Vaccines, 2021 - nature.com
We analyzed data from two ongoing COVID-19 longitudinal serological surveys in Orange
County, CA., between April 2020 and March 2021. A total of 8476 finger stick blood …

Omicron-specific mRNA vaccine induced potent neutralizing antibody against Omicron but not other SARS-CoV-2 variants

IJ Lee, CP Sun, PY Wu, YH Lan, IH Wang, WC Liu… - BioRxiv, 2022 - biorxiv.org
The emerging SARS-CoV-2 variants of concern (VOC) harbor mutations associated with
increasing transmission and immune escape, hence undermine the effectiveness of current …