The bHLH-PAS (basic helix-loop-helix/Period-ARNT-Single minded) proteins are a family of
transcriptional regulators commonly occurring in living organisms. bHLH-PAS members act …

The basic helix–loop–helix/Per-ARNT-SIM (bHLH–PAS) proteins are a class of
transcriptional regulators, commonly occurring in living organisms and highly conserved …

The binding affinity between a nuclear localization signal (NLS) and its import receptor is
closely related to corresponding nuclear import activity. PTM‐based modulation of the NLS …

Background Appropriate protein subcellular localization is essential for proper cellular
function. Central to the regulation of protein localization are protein targeting motifs …

A nuclear export signal (NES) is a protein localization signal, which is involved in binding of
cargo proteins to nuclear export receptor, thus contributes to regulate localization of cellular …

Proteins share peptidic sequences, such as a nuclear localization signal (NLS), which guide
them to particular membrane-bound compartments. Similarities have also been observed …

We present a thorough analysis of nuclear export signals and a prediction server, which we
have made publicly available. The machine learning prediction method is a significant …

Nuclear translocation of large proteins is mediated through karyopherins, carrier proteins
recognizing specific motifs of cargo proteins, known as nuclear localization signals (NLS) …

Histone chaperone proteins assist in the formation of the histone octamers, the scaffold
proteins that facilitate the packing of DNA into nucleosomes in the cell nucleus. One such …

Most transcription and epigenetic factors in eukaryotic cells have nuclear localization signals
(NLSs) and are transported to the nucleus by nuclear transport proteins. Understanding the …