The prospect of genomic, transcriptomic, epigenetic and metabolomic biomarkers for the personalized prevention of type 2 diabetes and cardiovascular diseases

A Zeljkovic, M Mihajlovic, S Vujcic… - Current Vascular …, 2023 - ingentaconnect.com
Cardiometabolic diseases, such as type 2 diabetes mellitus (DM) and cardiovascular
disease (CVD), are a great health concern. The strategies aimed to increase awareness and …

Metabolomic prediction of diabetes and cardiovascular risk

S Dagogo-Jack - Medical Principles and Practice, 2012 - karger.com
Type 2 diabetes mellitus (T2DM), currently an epidemic, is expected to disproportionately
affect developing countries in the coming decades [1]. Thus, primary prevention of T2DM is a …

Metabolomics for biomarkers of type 2 diabetes mellitus: advances and nutritional intervention trends

M Urpi-Sarda, E Almanza-Aguilera, S Tulipani… - Current cardiovascular …, 2015 - Springer
Metabolic characterization of type 2 diabetes mellitus (T2DM) is crucial for the identification
of individuals at risk for developing diabetes and T2DM-related vascular complications as …

The discovery of novel genomic, transcriptomic, and proteomic biomarkers in cardiovascular and peripheral vascular disease: the state of the art

S De Franciscis, L Metzinger… - BioMed research …, 2016 - Wiley Online Library
Cardiovascular disease (CD) and peripheral vascular disease (PVD) are leading causes of
mortality and morbidity in western countries and also responsible of a huge burden in terms …

Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function

SH Shah, WE Kraus, CB Newgard - Circulation, 2012 - Am Heart Assoc
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, but their
molecular etiology remains poorly understood, in part because they develop slowly as a …

Translational and emerging clinical applications of metabolomics in cardiovascular disease diagnosis and treatment

AC Dona, S Coffey, G Figtree - European Journal of …, 2016 - journals.sagepub.com
Numerous molecular screening strategies have recently been developed to measure the
chemical diversity of a population's biofluids with the ultimate aim to provide clinicians …

Metabolomics through the lens of precision cardiovascular medicine

SM Lam, Y Wang, B Li, J Du, G Shui - Journal of genetics and genomics, 2017 - Elsevier
Metabolomics, which targets at the extensive characterization and quantitation of global
metabolites from both endogenous and exogenous sources, has emerged as a novel …

On the road to accurate biomarkers for cardiometabolic diseases by integrating precision and gender medicine approaches

L Scola, RM Giarratana, S Torre, V Argano… - International journal of …, 2019 - mdpi.com
The need to facilitate the complex management of cardiometabolic diseases (CMD) has led
to the detection of many biomarkers, however, there are no clear explanations of their role in …

Metabolic phenotyping and cardiovascular disease: an overview of evidence from epidemiological settings

A Iliou, E Mikros, I Karaman, F Elliott, JL Griffin… - Heart, 2021 - heart.bmj.com
Metabolomics, the comprehensive measurement of low-molecular-weight molecules in
biological fluids used for metabolic phenotyping, has emerged as a promising tool to better …

Metabolomics: ready for the prime time?

M Mayr - Circulation: Cardiovascular Genetics, 2008 - Am Heart Assoc
Metabolomics is one of the most rapidly growing areas of contemporary science. Although
classic genetics aims to link variations in the DNA sequence directly to distinct phenotypes,“ …