[HTML][HTML] The favorable impacts of silibinin polyphenols as adjunctive therapy in reducing the complications of COVID-19: A review of research evidence and …

V Musazadeh, A Karimi, J Jafarzadeh, S Sanaie… - Biomedicine & …, 2022 - Elsevier
The proceeding pandemic of coronavirus disease 2019 is the latest global challenge. Like
most other infectious diseases, inflammation, oxidative stress, and immune system …

Comparative evaluation of flavonoids reveals the superiority and promising inhibition activity of silibinin against SARS‐CoV‐2

R Hamdy, A Mostafa, NM Abo Shama… - Phytotherapy …, 2022 - Wiley Online Library
Flavonoids are phenolic compounds naturally found in plants and commonly consumed in
diets. Herein, flavonoids were sequentially evaluated by a comparative in silico study …

[HTML][HTML] Anti-viral activity of bioactive molecules of silymarin against COVID-19 via in silico studies

C Zhang, Y Sui, S Liu, M Yang - Pharmaceuticals, 2023 - mdpi.com
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection drove the
global coronavirus disease 2019 (COVID-19) pandemic, causing a huge loss of human life …

Evaluation of the efficacy of oral nano‐silymarin formulation in hospitalized patients with COVID‐19: A double‐blind placebo‐controlled clinical trial

H Aryan, RH Farahani, M Chamanara… - Phytotherapy …, 2022 - Wiley Online Library
Considering the outbreak pandemic of Coronavirus Disease 2019 (COVID‐19), the lack of
effective therapeutic strategies for the management of this viral disease, and the increasing …

Phyto‐pharmacological perspective of Silymarin: A potential prophylactic or therapeutic agent for COVID‐19, based on its promising immunomodulatory, anti …

P Palit, A Mukhopadhyay… - Phytotherapy …, 2021 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) triggered by a new viral pathogen, named severe
acute respiratory syndrome Coronavirus‐2 (SARS‐CoV‐2), is now a global health …

An overview of possible pivotal mechanisms of Genistein as a potential phytochemical against SARS‐CoV‐2 infection: A hypothesis

A Jafari, Z Esmaeilzadeh, MR Khezri… - Journal of Food …, 2022 - Wiley Online Library
Abstract The Coronavirus Disease 2019 (COVID‐19) pandemic has been caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It is a global problem that …

[HTML][HTML] Flavonoids as promising antiviral agents against SARS-CoV-2 infection: a mechanistic review

MA Khazeei Tabari, A Iranpanah, R Bahramsoltani… - Molecules, 2021 - mdpi.com
A newly diagnosed coronavirus in 2019 (COVID-19) has affected all human activities since
its discovery. Flavonoids commonly found in the human diet have attracted a lot of attention …

[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm

A Liskova, M Samec, L Koklesova, SM Samuel… - Biomedicine & …, 2021 - Elsevier
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …

A comprehensive review on modulation of SIRT1 signaling pathways in the immune system of COVID‐19 patients by phytotherapeutic melatonin and epigallocatechin …

V Chattree, K Singh, K Singh, A Goel… - Journal of food …, 2022 - Wiley Online Library
SARS‐CoV‐2 infection has now become the world's most significant health hazard, with the
World Health Organization declaring a pandemic on March 11, 2020. COVID‐19 enters the …

Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS‐CoV‐2

A Gour, D Manhas, S Bag, B Gorain… - Phytotherapy …, 2021 - Wiley Online Library
Emergence of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection,
COVID‐19, has become the global panic since December 2019, which urges the global …