The artificial intelligence clinician learns optimal treatment strategies for sepsis in intensive care

M Komorowski, LA Celi, O Badawi, AC Gordon… - Nature medicine, 2018 - nature.com
Sepsis is the third leading cause of death worldwide and the main cause of mortality in
hospitals,–, but the best treatment strategy remains uncertain. In particular, evidence …

Individualized sepsis treatment using reinforcement learning

S Saria - Nature medicine, 2018 - nature.com
Individualized sepsis treatment using reinforcement learning | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Clinical management of sepsis can be improved by artificial intelligence: yes

M Komorowski - Intensive care medicine, 2020 - Springer
The management of sepsis is a highly complex, multifaceted challenge that remains the
realm of highly skilled and trained human experts. But as medical applications of artificial …

Deep reinforcement learning for sepsis treatment

A Raghu, M Komorowski, I Ahmed, L Celi… - arXiv preprint arXiv …, 2017 - arxiv.org
Sepsis is a leading cause of mortality in intensive care units and costs hospitals billions
annually. Treating a septic patient is highly challenging, because individual patients …

Continuous state-space models for optimal sepsis treatment: a deep reinforcement learning approach

A Raghu, M Komorowski, LA Celi… - Machine Learning …, 2017 - proceedings.mlr.press
Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals
billions annually. Treating a septic patient is highly challenging, because individual patients …

[HTML][HTML] Improving sepsis treatment strategies by combining deep and kernel-based reinforcement learning

X Peng, Y Ding, D Wihl, O Gottesman… - AMIA Annual …, 2018 - ncbi.nlm.nih.gov
Sepsis is the leading cause of mortality in the ICU. It is challenging to manage because
individual patients respond differently to treatment. Thus, tailoring treatment to the individual …

Ignore, trust, or negotiate: understanding clinician acceptance of AI-based treatment recommendations in health care

V Sivaraman, LA Bukowski, J Levin, JM Kahn… - Proceedings of the …, 2023 - dl.acm.org
Artificial intelligence (AI) in healthcare has the potential to improve patient outcomes, but
clinician acceptance remains a critical barrier. We developed a novel decision support …

Deep reinforcement learning and simulation as a path toward precision medicine

BK Petersen, J Yang, WS Grathwohl… - Journal of …, 2019 - liebertpub.com
Traditionally, precision medicine involves classifying patients to identify subpopulations that
respond favorably to specific therapeutics. We pose precision medicine as a dynamic …

A value-based deep reinforcement learning model with human expertise in optimal treatment of sepsis

XD Wu, RC Li, Z He, TZ Yu, CQ Cheng - NPJ Digital Medicine, 2023 - nature.com
Abstract Deep Reinforcement Learning (DRL) has been increasingly attempted in assisting
clinicians for real-time treatment of sepsis. While a value function quantifies the performance …

Deep inverse reinforcement learning for sepsis treatment

C Yu, G Ren, J Liu - 2019 IEEE international conference on …, 2019 - ieeexplore.ieee.org
Sepsis is a leading cause of mortality in hospitals, but its optimal treatment strategy still
remains unclear. Recent years have witnessed several successful applications of …