Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil

NR Faria, TA Mellan, C Whittaker, IM Claro… - Science, 2021 - science.org
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …

[HTML][HTML] Genomic surveillance of SARS-CoV-2 tracks early interstate transmission of P. 1 lineage and diversification within P. 2 clade in Brazil

AP Lamarca, LGP de Almeida… - PLoS neglected …, 2021 - journals.plos.org
The sharp increase of COVID-19 cases in late 2020 has made Brazil the new epicenter of
the ongoing SARS-CoV-2 pandemic. The novel viral lineages P. 1 (Variant of Concern …

[HTML][HTML] Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil

M Giovanetti, SN Slavov, V Fonseca, E Wilkinson… - Nature …, 2022 - nature.com
The high numbers of COVID-19 cases and deaths in Brazil have made Latin America an
epicentre of the pandemic. SARS-CoV-2 established sustained transmission in Brazil early …

[PDF][PDF] Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings

NR Faria, IM Claro, D Candido, LAM Franco… - Virological, 2021 - academia.edu
We have detected a new variant circulating in December in Manaus, Amazonas state, north
Brazil, where very high attack rates have been estimated previously. The new lineage …

Genomic characterization of a novel SARS-CoV-2 lineage from Rio de Janeiro, Brazil

CM Voloch, R da Silva Francisco Jr… - Journal of …, 2021 - Am Soc Microbiol
Almost simultaneously, several studies reported the emergence of novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages characterized by distinct …

[HTML][HTML] Genomic epidemiology of SARS-CoV-2 in Esteio, Rio Grande do Sul, Brazil

VB Franceschi, GD Caldana, A de Menezes Mayer… - BMC genomics, 2021 - Springer
Background Brazil is the third country most affected by Coronavirus disease-2019 (COVID-
19), but viral evolution in municipality resolution is still poorly understood in Brazil and it is …

[HTML][HTML] COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P. 1 emergence

FG Naveca, V Nascimento, VC de Souza, AL Corado… - Nature medicine, 2021 - nature.com
The northern state of Amazonas is among the regions in Brazil most heavily affected by the
COVID-19 epidemic and has experienced two exponentially growing waves, in early and …

Spread of Gamma (P. 1) sub-lineages carrying Spike mutations close to the furin cleavage site and deletions in the N-terminal domain drives ongoing transmission of …

FG Naveca, V Nascimento, V Souza… - Microbiology …, 2022 - Am Soc Microbiol
The Amazonas was one of the most heavily affected Brazilian states by the COVID-19
epidemic. Despite a large number of infected people, particularly during the second wave …

[HTML][HTML] Public health actions to control new SARS-CoV-2 variants

ND Grubaugh, EB Hodcroft, JR Fauver, AL Phelan… - Cell, 2021 - cell.com
Recent reports suggest that some SARS-CoV-2 genetic variants, such as B. 1.1. 7, might be
more transmissible and are quickly spreading around the world. As the emergence of more …

[HTML][HTML] The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …