[HTML][HTML] Grey-matter structure in cortical and limbic regions correlates with general cognitive ability in old age

Y Köhncke, S Kühn, S Düzel, MC Sander… - Aging Brain, 2024 - Elsevier
According to the maintenance hypothesis (Nyberg et al., 2012), structural integrity of the
brain's grey matter helps to preserve cognitive functioning into old age. A corollary of this …

Structural MRI covariance patterns associated with normal aging and neuropsychological functioning

AM Brickman, C Habeck, E Zarahn, J Flynn… - Neurobiology of aging, 2007 - Elsevier
Structural magnetic resonance imaging (MRI) studies have shown dramatic age-associated
changes in grey and white matter volume, but typically use univariate analyses that do not …

Gray-matter macrostructure in cognitively healthy older persons: associations with age and cognition

DA Fleischman, S Leurgans, K Arfanakis… - Brain Structure and …, 2014 - Springer
A deeper understanding of brain macrostructure and its associations with cognition in
persons who are considered cognitively healthy is critical to the early detection of persons at …

Disconnected aging: cerebral white matter integrity and age-related differences in cognition

IJ Bennett, DJ Madden - Neuroscience, 2014 - Elsevier
Cognition arises as a result of coordinated processing among distributed brain regions and
disruptions to communication within these neural networks can result in cognitive …

Differential predictability of cognitive profiles from brain structure in older males and females

C Jockwitz, C Krämer, P Dellani, S Caspers - GeroScience, 2024 - Springer
Structural brain imaging parameters may successfully predict cognitive performance in
neurodegenerative diseases but mostly fail to predict cognitive abilities in healthy older …

Joint contributions of cortical morphometry and white matter microstructure in healthy brain aging: a partial least squares correlation analysis

DA Hoagey, JR Rieck, KM Rodrigue… - Human Brain …, 2019 - Wiley Online Library
Cortical atrophy and degraded axonal health have been shown to coincide during normal
aging; however, few studies have examined these measures together. To lend insight into …

[HTML][HTML] Inter-and intra-individual variation in brain structural-cognition relationships in aging

R Patel, CE Mackay, MG Jansen, GA Devenyi… - NeuroImage, 2022 - Elsevier
The sources of inter-and intra-individual variability in age-related cognitive decline remain
poorly understood. We examined the association between 20-year trajectories of cognitive …

The impact of aging on gray matter structural covariance networks

M Montembeault, S Joubert, J Doyon, J Carrier… - Neuroimage, 2012 - Elsevier
Previous anatomical volumetric studies have shown that healthy aging is associated with
gray matter tissue loss in specific cerebral regions. However, these studies may have …

Differential age-dependent associations of gray matter volume and white matter integrity with processing speed in healthy older adults

Z Hong, KK Ng, SKY Sim, MY Ngeow, H Zheng, JC Lo… - Neuroimage, 2015 - Elsevier
Slower processing speed (PS), a highly robust feature of cognitive aging, is associated with
white matter (WM) deterioration and gray matter volume (GMV) loss. Traditional linear …

Gray matter volume and cognitive performance during normal aging. A voxel-based morphometry study

S Ramanoël, E Hoyau, L Kauffmann… - Frontiers in aging …, 2018 - frontiersin.org
Normal aging is characterized by decline in cognitive functioning in conjunction with
extensive gray matter (GM) atrophy. A first aim of this study was to determine GM volume …