Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights
Bipolar disorder (BD) is a heritable mental illness with complex etiology. We performed a
genome-wide association study (GWAS) of 41,917 BD cases and 371,549 controls of …
genome-wide association study (GWAS) of 41,917 BD cases and 371,549 controls of …
Genome-wide association study identifies 30 loci associated with bipolar disorder
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent …
association study (GWAS) including 20,352 cases and 31,358 controls of European descent …
The genetics of bipolar disorder
FJA Gordovez, FJ McMahon - Molecular psychiatry, 2020 - nature.com
Bipolar disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …
Genetic contributions to bipolar disorder: current status and future directions
KS O'Connell, BJ Coombes - Psychological Medicine, 2021 - cambridge.org
Bipolar disorder (BD) is a highly heritable mental disorder and is estimated to affect about 50
million people worldwide. Our understanding of the genetic etiology of BD has greatly …
million people worldwide. Our understanding of the genetic etiology of BD has greatly …
Identification of pathways for bipolar disorder: a meta-analysis
Importance Genome-wide investigations provide systematic information regarding the
neurobiology of psychiatric disorders. Objective To identify biological pathways that …
neurobiology of psychiatric disorders. Objective To identify biological pathways that …
Genetics of bipolar disorder
B Kerner - The application of clinical genetics, 2014 - Taylor & Francis
Bipolar disorder is a common, complex genetic disorder, but the mode of transmission
remains to be discovered. Many researchers assume that common genomic variants carry …
remains to be discovered. Many researchers assume that common genomic variants carry …
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder
Bipolar disorder (BD) is a genetically complex mental illness characterized by severe
oscillations of mood and behaviour. Genome-wide association studies (GWAS) have …
oscillations of mood and behaviour. Genome-wide association studies (GWAS) have …
Convergent functional genomics of genome‐wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms
H Le‐Niculescu, SD Patel, M Bhat… - American Journal of …, 2009 - Wiley Online Library
Given the mounting convergent evidence implicating many more genes in complex
disorders such as bipolar disorder than the small number identified unambiguously by the …
disorders such as bipolar disorder than the small number identified unambiguously by the …
Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate
Bipolar disorder is a common, heritable mental illness characterized by recurrent episodes
of mania and depression. Despite considerable effort to elucidate the genetic underpinnings …
of mania and depression. Despite considerable effort to elucidate the genetic underpinnings …