Abstract Background Natriuretic peptides (NPs) represent a critical pathway in heart failure
(HF). However, there is wide individual variability in NP system activity, which could be partly …

Abstract Purpose of Review Heart failure (HF) continues to be a public health burden
despite advances in therapy, and the natriuretic peptide (NP) system is clearly of critical …

Heart failure (HF) is a modern epidemic and is one of the few cardiovascular diseases which
is increasing in prevalence. The growing importance of the Natriuretic Peptide (NP) system …

Natriuretic peptides (NPs) represent a critical pathway in heart failure (HF). We explored
genetic determinants of pharmacodynamic effects of B-type NP (BNP) and changes in …

Background Subclinical volume overload in the absence of diagnosed heart failure (HF)
may be an underrecognized contributor to kidney function decline in coronary artery disease …

Purpose The importance of B-type natriuretic peptide (BNP) as a diagnostic and therapeutic
modality in cardiovascular disease is well known. BNP levels correlate clinical and …

Aims N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) is the most frequently used
biomarker in heart failure (HF), but its prognostic utility across ethnicities is unclear. Methods …

Background Elevated B‐type natriuretic peptide (BNP) levels are associated with heart
failure and increased mortality in the general population. We investigated rs198389, a …

Background: B-type natriuretic peptide levels are associated with left ventricular end-
diastolic pressure (LVEDP) and patient outcomes. There is documented variation in the …

Over the years, substantial progress has been made in the understanding and treatment of
heart failure (HF). Multiple distinct pathophysiological mechanisms have been shown to …