Altered fecal bile acid composition in active ulcerative colitis

S Sommersberger, S Gunawan, T Elger… - Lipids in Health and …, 2023 - Springer
Background Disturbed bile acid homeostasis associated with a rise of primary and a decline
of secondary bile acids is a consistent finding in inflammatory bowel diseases (IBDs) …

[HTML][HTML] Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis

ZH Yang, F Liu, XR Zhu, FY Suo, Z Jia… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Gut microbiota and its metabolites may be involved in the pathogenesis of
inflammatory bowel disease. Several clinical studies have recently shown that patients with …

Bile acid alterations associated with indolent course of inflammatory bowel disease

C Liu, S Zhan, N Li, T Tu, J Lin, M Li… - Scandinavian Journal …, 2023 - Taylor & Francis
Background The indolent course of treatment-naive patients with inflammatory bowel
disease (IBD) is confirmed predictable based on clinical characteristics. Current evidences …

[HTML][HTML] Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease

C Gnewuch, G Liebisch, T Langmann… - World journal of …, 2009 - ncbi.nlm.nih.gov
AIM: To determine free and conjugated serum bile acid (BA) levels in inflammatory bowel
disease (IBD) subgroups with defined clinical manifestations. METHODS: Comprehensive …

Concentrations of fecal bile acids in participants with functional gut disorders and healthy controls

SC James, K Fraser, W Young, PE Heenan, RB Gearry… - Metabolites, 2021 - mdpi.com
Bile acids are metabolites involved in nutrient absorption and signaling with levels
influenced by dietary intake, metabolic processes, and the gut microbiome. We aimed to …

Bile acids as inflammatory mediators and modulators of intestinal permeability

N Calzadilla, SM Comiskey, PK Dudeja… - Frontiers in …, 2022 - frontiersin.org
Bile acids are critical for the digestion and absorption of lipids and fat-soluble vitamins;
however, evidence continues to emerge supporting additional roles for bile acids as …

[HTML][HTML] Relationship between the gut microbiota and bile acid composition in the ileal mucosa of Crohn's disease

S Bamba, O Inatomi, A Nishida, M Ohno, T Imai… - Intest …, 2022 - synapse.koreamed.org
Methods Twelve non-CD controls and 38 CD patients in clinical remission were enrolled.
Samples were collected from the distal ileum under balloon-assisted enteroscopy. Bile acid …

The pathophysiology of bile acid diarrhoea: differences in the colonic microbiome, metabolome and bile acids

NM Sagar, H Duboc, GL Kay, MT Alam… - Scientific reports, 2020 - nature.com
Bile acid diarrhoea (BAD) is a common disorder resulting from increased loss of bile acids
(BAs), overlapping irritable bowel syndrome with diarrhoea (IBS-D). The gut microbiota …

Systematic review: bile acids and intestinal inflammation‐luminal aggressors or regulators of mucosal defence?

P Pavlidis, N Powell, RP Vincent… - Alimentary …, 2015 - Wiley Online Library
Background Inflammatory bowel diseases (IBD), comprising Crohn's disease and ulcerative
colitis (UC), are chronic conditions attributed to an aberrant immune response to luminal …

A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis

BP Vaughn, T Kaiser, C Staley… - Clinical and …, 2019 - Taylor & Francis
Introduction Inflammatory bowel disease (IBD) is thought to arise from an abnormal immune
response to the gut microbiota. IBD is associated with altered intestinal microbial community …