Background Longitudinal trajectories of asthma and allergies from childhood to adulthood
might be differentially associated with lung function and chronic obstructive pulmonary …

Background Lifetime lung function is related to quality of life and longevity. Over the lifespan,
individuals follow different lung function trajectories. Identification of these trajectories, their …

Rationale: Asthma is a heterogeneous condition, and longitudinal phenotyping may provide
new insights into the origins and outcomes of the disease. Objectives: We aimed to …

Background Differences between early-onset and late-onset adult asthma have not been
comprehensively described using prospective data. Aims To characterise the differences …

Background Long-term prognosis of patients with characteristics of both chronic obstructive
pulmonary disease (COPD) and asthma, named asthma-COPD overlap, is poorly described …

Asthma is the most prevalent chronic respiratory disease both in children and adults and
resembles a complex syndrome rather than a single disease. Different methods have been …

Background Asthma-onset in older individuals has been associated with an accelerated
decline in lung function, but direct comparisons with younger adults have not been reported …

Background Asthma can occur at any age but the differences in patient characteristics
between childhood-, adult-, and late-onset asthma are not well understood. Objective To …

Background Research based on cluster analyses led to the identification of particular
phenotypes confirming phenotypic heterogeneity of asthma. The long‐term clinical course of …

Background Change in the prevalence of asthma-like symptoms in populations of ageing
adults is likely to be influenced by smoking, asthma treatment and atopy. Methods The …