The coronavirus (CoV) spike (S) protein, involved in viral–host cell fusion, is the primary
immunogenic target for virus neutralization and the current focus of many vaccine design …

Various human pathogenic viruses employ envelope glycoproteins for host cell receptor
recognition and binding, membrane fusion and viral entry. The spike (S) glycoprotein of …

The spike (S) protein of SARS-CoV-2 mediates receptor binding and cell entry and is the
dominant target of the immune system. It exhibits substantial conformational flexibility. It …

The SARS-CoV-2 S protein is a major point of interaction between the virus and the human
immune system. As a consequence, the S protein is not a static target but undergoes rapid …

SARS-CoV-2 is the causative agent of the COVID-19 pandemic, with 10 million infections
and more than 500,000 fatalities by June 2020. To initiate infection, the SARS-CoV-2 spike …

Intervention strategies are urgently needed to control the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) pandemic. The trimeric viral spike (S) protein catalyzes fusion …

The global pandemic of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has significantly affected every human life and overloaded the …

The spike protein (S-protein) of SARS-CoV-2, the protein that enables the virus to infect
human cells, is the basis for many vaccines and a hotspot of concerning virus evolution …

Abstract The SARS-CoV-2 spike (S) protein, a primary target for COVID-19 vaccine
development, presents its receptor binding domain in two conformations, the receptor …

The worldwide pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is unprecedented and the impact on public health and the global economy …