CD300e: Emerging role and mechanism as an immune-activating receptor

N Liu, W Sun, W Gao, S Yan, C Yang, J Zhang… - International …, 2024 - Elsevier
As a transmembrane protein, CD300e is primarily expressed in myeloid cells. It belongs to
the CD300 glycoprotein family, functioning as an immune-activating receptor. Dysfunction of …

CD300a and CD300f molecules regulate the function of leukocytes

Y Cao, T Ao, X Wang, W Wei, J Fan, X Tian - International …, 2021 - Elsevier
The CD300 molecule family is a type I transmembrane glycoprotein expressed on cell
membrane of human and other mammals, and of its eight members, only CD300a and …

The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions

GJ Clark, X Ju, C Tate, DNJ Hart - Trends in immunology, 2009 - cell.com
The CD300 glycoproteins are a family of cell surface molecules that modulate a diverse
array of cell processes via their paired triggering and inhibitory receptor functions. Family …

The CD300 molecules: an emerging family of regulators of the immune system

F Borrego - Blood, The Journal of the American Society of …, 2013 - ashpublications.org
The CD300 family of molecules modulates a broad and diverse array of immune cell
processes via their paired activating and inhibitory receptor functions. The description that …

The biology and disease relevance of CD300a, an inhibitory receptor for phosphatidylserine and phosphatidylethanolamine

O Zenarruzabeitia, J Vitallé, C Eguizabal… - The Journal of …, 2015 - journals.aai.org
The CD300a inhibitory receptor belongs to the CD300 family of cell surface molecules that
regulate a diverse array of immune cell processes. The inhibitory signal of CD300a depends …

The immune receptor CD300e negatively regulates T cell activation by impairing the STAT1-dependent antigen presentation

S Coletta, V Salvi, C Della Bella, A Bertocco… - Scientific reports, 2020 - nature.com
CD300e is a surface receptor, expressed by myeloid cells, involved in the tuning of immune
responses. CD300e engagement was reported to provide the cells with survival signals, to …

The CD300 molecules regulate monocyte and dendritic cell functions

GJ Clark, X Ju, M Azlan, C Tate, Y Ding, DNJ Hart - Immunobiology, 2009 - Elsevier
The CD300 glycoproteins are a family of related leucocyte surface molecules that modulate
a diverse array of cell processes via their paired triggering and inhibitory receptor functions …

Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells

T Brckalo, F Calzetti, B Pérez‐Cabezas… - European journal of …, 2010 - Wiley Online Library
The CD300e surface molecule, originally termed immune receptor expressed by myeloid
cells (IREM)‐2, was reported to associate with the DNAX‐activating protein (DAP) 12 …

CD300 molecule regulation of human dendritic cell functions

RE Gasiorowski, X Ju, DNJ Hart, GJ Clark - Immunology letters, 2013 - Elsevier
Dendritic cells (DC) are a heterogeneous population of leucocytes which play a key role in
initiating and modulating immune responses. The human CD300 family consists of six …

The CD300e molecule in mice is an immune-activating receptor

M Isobe, K Izawa, M Sugiuchi, T Sakanishi… - Journal of Biological …, 2018 - ASBMB
CD300 molecules (CD300s) belong to paired activating and inhibitory receptor families,
which mediate immune responses. Human CD300e (hCD300e) is expressed in monocytes …