Exploring potential biomarkers and therapeutic targets in inflammatory bowel disease: insights from a mega-analysis approach
E Stemmer, T Zahavi, M Kellerman… - Frontiers in …, 2024 - frontiersin.org
Background Understanding the molecular pathogenesis of inflammatory bowel disease
(IBD) has led to the discovery of new therapeutic targets that are more specific and effective …
(IBD) has led to the discovery of new therapeutic targets that are more specific and effective …
[HTML][HTML] Delineating inflammatory bowel disease through transcriptomic studies: current review of progress and evidence
Inflammatory bowel disease (IBD), which comprises of Crohn's disease and ulcerative
colitis, is an idiopathic relapsing and remitting disease in which the interplay of different …
colitis, is an idiopathic relapsing and remitting disease in which the interplay of different …
Molecular analysis of inflammatory bowel disease: clinically useful tools for diagnosis, response prediction, and monitoring of targeted therapy
W Jiang, X Li - Molecular diagnosis & therapy, 2015 - Springer
Biomarkers of inflammatory bowel disease (IBD) are non-invasive or minimally invasive tests
for IBD diagnosis and/or prognosis as well as assessment of disease activity and response …
for IBD diagnosis and/or prognosis as well as assessment of disease activity and response …
Transcriptome analysis identifies genetic risk markers and explores the pathogenesis for inflammatory bowel disease
J Wang, M Sun, X Liu, Q Yan, Q Gao, K Ni… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Inflammatory bowel disease (IBD) is an incurable and disabling bowel disease driven by
multiple risk factors that severely limit patients' quality of life. We integrated the RNA …
multiple risk factors that severely limit patients' quality of life. We integrated the RNA …
The inflammatory bowel disease transcriptome and metatranscriptome meta-analysis (IBD TaMMA) framework
Inflammatory bowel disease (IBD) is a class of chronic disorders whose etiogenesis is still
unknown. Despite the high number of IBD-related omics studies, the RNA-sequencing data …
unknown. Despite the high number of IBD-related omics studies, the RNA-sequencing data …
Precision medicine in IBD: genes, drugs, bugs and omics
R Mao, M Chen - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
Key studies published in 2021 demonstrated mechanisms that drive macrophage–fibroblast
pathogenicity in Crohn's disease, developed multi-omics profiles to predict response to …
pathogenicity in Crohn's disease, developed multi-omics profiles to predict response to …
Whole genome gene expression meta-analysis of inflammatory bowel disease colon mucosa demonstrates lack of major differences between Crohn's disease and …
Background In inflammatory bowel disease (IBD), genetic susceptibility together with
environmental factors disturbs gut homeostasis producing chronic inflammation. The two …
environmental factors disturbs gut homeostasis producing chronic inflammation. The two …
Multi-omics analysis of inflammatory bowel disease
Crohn's disease and ulcerative colitis, known together as inflammatory bowel disease (IBD),
are severe autoimmune disorders now causing gut inflammation and ulceration, among …
are severe autoimmune disorders now causing gut inflammation and ulceration, among …
Identification of novel mRNAs and lncRNAs associated with mouse experimental colitis and human inflammatory bowel disease
CR Rankin, E Theodorou, IK Man Law… - American Journal …, 2018 - journals.physiology.org
Inflammatory bowel disease (IBD) is a complex disorder that is associated with significant
morbidity. While many recent advances have been made with new diagnostic and …
morbidity. While many recent advances have been made with new diagnostic and …
Biomarkers of inflammation in inflammatory bowel disease
BE Sands - Gastroenterology, 2015 - Elsevier
Recent observations suggest that subjective measures of disease activity in inflammatory
bowel disease (IBD) are often misleading. Objective measures of inflammation are more …
bowel disease (IBD) are often misleading. Objective measures of inflammation are more …