Background Glomerular filtration rate (GFR) is the gold standard in assessing renal function
but is impractical. Serum creatinine (sCr) has limited sensitivity in identifying early chronic …

Background Symmetric dimethylarginine (SDMA) has been shown to be an accurate and
precise biomarker for calculating estimated glomerular filtration rate (GFR) in humans, as …

Background Direct measurement of glomerular filtration rate (GFR) is the preferred method
to assess renal function in cats, but it is not widely used in the diagnosis of chronic kidney …

Background Symmetric dimethylarginine (SDMA) is a small molecule formed by methylation
of arginine, and released into blood during protein degradation. SDMA is primarily …

Background Serum concentrations of symmetric dimethylarginine (SDMA) detected chronic
kidney disease (CKD) in cats an average of 17.0 months before serum creatinine (Cr) …

Background Early detection of decreased glomerular filtration rate (GFR) in dogs is
challenging. Current methods are insensitive and new biomarkers are required. Objective …

Background Serum symmetric dimethylarginine (SDMA) concentrations are considered a
biomarker for renal dysfunction in dogs and humans with acute kidney injury (AKI). No …

Symmetric dimethylarginine (SDMA) is a sensitive surrogate marker for glomerular filtration
rate; however, there are uncertainties as to how to interpret mild increases (SDMA 15–19 …

Background Serum creatinine and symmetric dimethylarginine (SDMA) are used as
surrogate markers of glomerular filtration rate (GFR) in clinical practice. Data pertaining to …

Background Symmetric dimethylarginine (SDMA) is considered a biomarker for early
detection of renal dysfunction in human patients with acute kidney injury (AKI). At present, no …