Importance The risk of birth and neurodevelopmental complications with prenatal exposure
to antipsychotics is unclear. Objective To evaluate the association between prenatal …

Importance Although antipsychotic drugs cross the placenta and animal data suggest
potential neurotoxic effects, information regarding human neurodevelopmental …

Importance The frequency of antipsychotic (AP) use during pregnancy has approximately
doubled during the last decade. However, little is known about their safety for the developing …

Importance Prenatal antidepressant exposure has been associated with adverse outcomes.
Previous studies, however, may not have adequately accounted for confounding. Objective …

Importance Antidepressant use during pregnancy has been associated with
neurodevelopmental disorders in children in some studies. However, results may be …

Importance Psychiatric disorders are common among female individuals of reproductive
age. While antipsychotic medication use is increasing, the safety of such medications in …

Objective To evaluate the association between antipsychotic use in pregnancy and the risk
of congenital malformations in children. Data sources Searches of PubMed, EMBASE …

Importance Maternal preeclampsia has been reported to increase the risk of autism
spectrum disorder, attention-deficit/hyperactivity disorder (ADHD), and intellectual disability …

OBJECTIVE: Antipsychotic medications are used by increasing numbers of women of
reproductive age. The safety of these medications during pregnancy has not been well …

Importance Valproate is an antiepileptic drug (AED) used in the treatment of epilepsy and
many other neurological and psychiatric disorders. Its use in pregnancy is associated with …