Image guided personalization of reaction-diffusion type tumor growth models using modified anisotropic eikonal equations

E Konukoglu, O Clatz, BH Menze… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
Reaction-diffusion based tumor growth models have been widely used in the literature for
modeling the growth of brain gliomas. Lately, recent models have started integrating medical …

A recursive anisotropic fast marching approach to reaction diffusion equation: Application to tumor growth modeling

E Konukoglu, M Sermesant, O Clatz, JM Peyrat… - … Processing in Medical …, 2007 - Springer
Bridging the gap between clinical applications and mathematical models is one of the new
challenges of medical image analysis. In this paper, we propose an efficient and accurate …

An image-driven parameter estimation problem for a reaction–diffusion glioma growth model with mass effects

C Hogea, C Davatzikos, G Biros - Journal of mathematical biology, 2008 - Springer
We present a framework for modeling gliomas growth and their mechanical impact on the
surrounding brain tissue (the so-called, mass-effect). We employ an Eulerian continuum …

Predicting in vivo glioma growth with the reaction diffusion equation constrained by quantitative magnetic resonance imaging data

DA Hormuth II, JA Weis, SL Barnes, MI Miga… - Physical …, 2015 - iopscience.iop.org
Reaction–diffusion models have been widely used to model glioma growth. However, it has
not been shown how accurately this model can predict future tumor status using model …

Glioma dynamics and computational models: a review of segmentation, registration, and in silico growth algorithms and their clinical applications

ED Angelini, O Clatz, E Mandonnet… - Current Medical …, 2007 - ingentaconnect.com
Tracking gliomas dynamics on MRI has became more and more important for therapeutic
management. Powerful computational tools have been recently developed in this context …

A generative approach for image-based modeling of tumor growth

BH Menze, K Van Leemput, A Honkela… - … Processing in Medical …, 2011 - Springer
Extensive imaging is routinely used in brain tumor patients to monitor the state of the
disease and to evaluate therapeutic options. A large number of multi-modal and multi …

An inverse problem formulation for parameter estimation of a reaction–diffusion model of low grade gliomas

A Gholami, A Mang, G Biros - Journal of mathematical biology, 2016 - Springer
We present a numerical scheme for solving a parameter estimation problem for a model of
low-grade glioma growth. Our goal is to estimate the spatial distribution of tumor …

The integration of quantitative multi-modality imaging data into mathematical models of tumors

NC Atuegwu, JC Gore… - Physics in Medicine & …, 2010 - iopscience.iop.org
Quantitative imaging data obtained from multiple modalities may be integrated into
mathematical models of tumor growth and treatment response to achieve additional insights …

A mechanically coupled reaction–diffusion model that incorporates intra-tumoural heterogeneity to predict in vivo glioma growth

DA Hormuth, JA Weis, SL Barnes… - Journal of The …, 2017 - royalsocietypublishing.org
While gliomas have been extensively modelled with a reaction–diffusion (RD) type equation
it is most likely an oversimplification. In this study, three mathematical models of glioma …

Hybrid mathematical model of glioma progression

ML Tanaka, W Debinski, IK Puri - Cell proliferation, 2009 - Wiley Online Library
Objectives: Gliomas are an important form of brain cancer, with high mortality rate.
Mathematical models are often used to understand and predict their behaviour. However …