The initiation and maintenance of reproductive capacity in humans is dependent on pulsatile
secretion of the hypothalamic hormone GnRH. Congenital hypogonadotropic hypogonadism …

Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder caused by the
deficient production, secretion or action of gonadotropin-releasing hormone (GnRH), which …

The proper development and coordination of the hypothalamic-pituitary-gonadal (HPG) axis
are essential for normal reproductive competence. The key factor that regulates the function …

Congenital hypogonadotropic hypogonadism (CHH) results from abnormal gonadotropin
secretion, and it is characterized by impaired pubertal development. CHH is caused by …

Congenital hypogonadotropic hypogonadism (CHH) is characterized by lack of puberty and
infertility. Traditionally, it has been considered a life-long condition yet cases of reversibility …

Traditionally, idiopathic hypogonadotropic hypogonadism (IHH) is divided into two major
categories: Kallmann syndrome (KS) and normosmic IHH (nIHH). To date, inactivating …

Hypothalamic gonadotropin releasing hormone (GnRH) is a key player in normal puberty
and sexual development and function. Genetic causes of isolated hypogonadotropic …

The term “congenital hypogonadotropic hypogonadism”(CHH) refers to a group of disorders
featuring complete or partial pubertal failure due to insufficient secretion of the pituitary …

Congenital hypogonadotropic hypogonadism (CHH) causes pubertal failure and infertility in
both women and men due to partial or total secretory failure of the two pituitary …

Context: Idiopathic hypogonadotropic hypogonadism (IHH) with normal smell (normosmic
IHH) or anosmia (Kallmann syndrome) is associated with defects in the production or action …