TFOS DEWS II clinical trial design report

GD Novack, P Asbell, S Barabino, MVW Bergamini… - The ocular …, 2017 - Elsevier
The development of novel therapies for Dry Eye Disease (DED) is formidable, and relatively
few treatments evaluated have been approved for marketing. In this report, the …

Report of the TFOS/ARVO symposium on global treatments for dry eye disease: an unmet need

DA Sullivan, KM Hammitt, DA Schaumberg… - The ocular …, 2012 - Elsevier
Abstract In September 2010, a Symposium in Florence, Italy, was held to address the unmet
need for global treatments for dry eye disease (DED). It was sponsored by The Tear Film & …

Alternative therapies for dry eye disease

R Mittal, S Patel, A Galor - Current opinion in ophthalmology, 2021 - journals.lww.com
Alternative therapies for dry eye disease : Current Opinion in Ophthalmology Alternative
therapies for dry eye disease : Current Opinion in Ophthalmology Log in or Register Subscribe …

Dry eye disease treatment: a systematic review of published trials and a critical appraisal of therapeutic strategies

M Alves, EC Fonseca, MF Alves, LT Malki, GV Arruda… - The ocular …, 2013 - Elsevier
Dry eye disease (DED) treatment is an area of increasing complexity, with the emergence of
several new treatment agents in recent years. Evaluation of the efficacy of these agents is …

Dry eye disease: present challenges in the management and future trends

Z Al-Saedi, A Zimmerman, R Devi Bachu… - Current …, 2016 - ingentaconnect.com
Dry eye disease (DED) is a tear film disorder resulting in hyperosmolarity of the tear film and
inflammation of the ocular surface. DED is also referred to as keratoconjunctivitis sicca …

Report of the inaugural meeting of the TFOS i2= initiating innovation series: targeting the unmet need for dry eye treatment

W Chao, C Belmonte, JMB Del Castillo, AJ Bron… - The ocular …, 2016 - Elsevier
Abstract On March 21, 2015, a meeting was held in London, United Kingdom, to address the
progress in targeting the unmet need for dry eye disease (DED) treatment. The meeting …

Management and therapy of dry eye disease: report of the Management and Therapy Subcommittee of the International Dry Eye WorkShop (2007)

SC Pflugfelder, G Geerling… - Ocular …, 2007 - utsouthwestern.elsevierpure.com
The members of the Management and Therapy Subcommittee assessed current dry eye
therapies. Each member wrote a succinct evidence-based review on an assigned aspect of …

Emerging therapies for dry eye disease

L Mason, S Jafri, I Dortonne… - Expert opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction Dry Eye Disease (DED) is defined as a multifactorial disease of the
ocular surface characterized by a loss of homeostasis of the tear film, and a vicious cycle of …

Challenges and pitfalls in clinical trials of treatments for dry eye

GN Foulks - The ocular surface, 2003 - Elsevier
Clinical trials to evaluate the effectiveness of therapy for dry eye disease are challenging
because of the nature of the disease, the multiple palliative methods used by patients to …

Advances in understanding and managing dry eye disease

MA Lemp - American journal of ophthalmology, 2008 - Elsevier
PURPOSE: To present evidence from the literature and scientific meetings to support
fundamental changes in concepts regarding the prevalence, pathogenesis, definition …