The use of biomarkers is becoming increasingly intrinsic to the practice of medicine and
holds great promise for transforming the practice of rheumatology. Biomarkers have the …

Better biomarkers, ideally mechanistic ones, are needed to guide clinical decision making in
rheumatology. Although the use of next-generation techniques for biomarker discovery is …

This review examines the biomarker development process by using rheumatic disorders as
the disease model for discussion. We evaluate the current role of biomarkers in the practice …

Effective treatment of rheumatoid arthritis (RA) has been hampered by the heterogeneity of
the disease. Although early intervention can result in disease remission, it requires early …

It is anticipated that biomarkers support rheumatologists to judge a group of patients that can
improve the diagnosis and prognosis, and further facilitate appropriate and precise …

Abstract The 21st Century Cures Act, approved in the USA in December 2016, has
encouraged the establishment of the national Precision Medicine Initiative and the …

The utilization and identification of biomarkers in rheumatoid arthritis (RA) to facilitate timely
diagnosis and the optimal management of the disease is an area of active investigation. This …

In recent years, patient outcomes have improved dramatically with the availability of effective
treatments for the management of rheumatoid arthritis (RA). RA, however, is a …

The expanding array of drugs available for treating rheumatoid arthritis is creating
challenges in drug selection for the individual patient. The identification of biomarkers that …

Osteoarthritis (OA) is the most common form of arthritis globally and a major cause of pain,
physical disability, and loss of economic productivity, with currently no causal treatment …