S-100 proteins: basics and applications as biomarkers in animals with special focus on calgranulins (S100A8, A9, and A12)

JJ Cerón, A Ortín-Bustillo, MJ López-Martínez… - Biology, 2023 - mdpi.com
Simple Summary S100 proteins are a group of calcium-binding proteins which have a
similar molecular mass and share similarities in their amino acid sequence. They are …

Changes in S100A8/A9 and S100A12 and Their Comparison with Other Analytes in the Saliva of Pigs with Diarrhea Due to E. coli

A Ortín-Bustillo, M Botía, MJ López-Martínez… - Animals, 2023 - mdpi.com
Simple Summary S100A8/A9 (also known as calprotectin) and S100A12 (also known as
calgranulin C) are considered biomarkers of potential interest and are proteins members of …

Development and analytic validation of an immunoassay for the quantification of canine S100A12 in serum and fecal samples and its biological variability in serum …

RM Heilmann, DJ Lanerie, CG Ruaux… - Veterinary immunology …, 2011 - Elsevier
S100A12 (calgranulin C) is a Ca2+-binding protein that has been proposed to play a central
role in both innate and acquired immune responses. In humans, S100A12 has been …

Measurement of calprotectin (S100A8/A9) in the Saliva of Pigs: Validation Data of a commercially available automated assay and changes in Sepsis, inflammation …

MJ López-Martínez, S Martínez-Subiela, JJ Cerón… - Animals, 2023 - mdpi.com
Simple Summary Calprotectin (CALP, S100A8/A9) is a calcium and zinc-binding protein
involved in inflammation that has a wide range of proinflammatory functions, such as …

Recombinant bovine S100A8 and A9 enhance IL-1β secretion of interferon-gamma primed monocytes

M Koy, N Hambruch, J Hussen, C Pfarrer… - Veterinary immunology …, 2013 - Elsevier
Abstract Calgranulin A (S100A8) and B (S100A9) are found at high levels in inflamed tissue
and have been associated with acute and chronic inflammatory disorders. Calgranulins are …

Amino acid sequence determination of human S100A12 (P6, calgranulin C, CGRP, CAAF1) by tandem mass spectrometry

EC Ilg, H Troxler, DM Bürgisser, T Kuster… - Biochemical and …, 1996 - Elsevier
S100A12 has been isolated from human neutrophils. The molecular weight and the amino
acid sequence of S100A12 was determined by electrospray-mass spectrometry, tandem …

Purification and partial characterization of canine S100A12

RM Heilmann, JS Suchodolski, JM Steiner - Biochimie, 2010 - Elsevier
Canine S100A12 (cS100A12) is a calcium-binding protein of the S100 superfamily of EF-
hand proteins, and its expression is restricted to neutrophils and monocytes. Interaction of …

Subcellular localization of S100A11 (S100C, calgizzarin) in developing and adult avian skeletal muscles

C Arcuri, I Giambanco, R Bianchi, R Donato - Biochimica et Biophysica Acta …, 2002 - Elsevier
S100A11 is a member of a multigenic family of Ca2+-modulated proteins of the EF-hand
type. We studied the subcellular localization of S100A11 in developing and adult avian …

S100 proteins in autoinflammation

D Holzinger, C Kessel, D Foell - Textbook of Autoinflammation, 2019 - Springer
Among the putative markers for autoinflammatory diseases, studies on phagocyte-derived
S100 proteins (S100A8/A9, S100A12: calgranulins) are the most advanced to date …

Extraction, isolation, and concentration of calprotectin antigen (S100A8/S100A9) from granulocytes

T Nilsen, SH Haugen, A Larsson - Health science reports, 2018 - Wiley Online Library
Background Calprotectin is a promising biomarker for granulocyte activation. It is mainly
measured in faeces as a marker for inflammatory bowel disease. A limitation is that there is …