Protective Effects of the Chalcone-Based Derivative AN07 on Inflammation-Associated Myotube Atrophy Induced by Lipopolysaccharide

WY Fang, CL Lin, WH Chang, CH Chang… - International Journal of …, 2022 - mdpi.com
Inflammation is a major cause of skeletal muscle atrophy in various diseases. 2-Hydroxy-4′-
methoxychalcone (AN07) is a chalcone-based peroxisome-proliferator-activated receptor …

BST204 protects dexamethasone-induced myotube atrophy through the upregulation of myotube formation and mitochondrial function

R Kim, H Kim, M Im, SK Park, HJ Han, S An… - International Journal of …, 2021 - mdpi.com
BST204 is a purified ginseng dry extract that has an inhibitory effect on lipopolysaccharide-
induced inflammatory responses, but its effect on muscle atrophy is yet to be investigated. In …

Protective Effect of Pyropia yezoensis Peptide on Dexamethasone-Induced Myotube Atrophy in C2C12 Myotubes

MK Lee, JW Choi, YH Choi, TJ Nam - Marine drugs, 2019 - mdpi.com
Dexamethasone (DEX), a synthetic glucocorticoid, causes skeletal muscle atrophy. This
study examined the protective effects of Pyropia yezoensis peptide (PYP15) against DEX …

18-Carbon polyunsaturated fatty acids via down-regulation NF-κB activation reduce lipopolysaccharide-induced myotube atrophy

PY Chen, HL Sun, YC Lin, CC Li, HW Chen, TS Wang… - RSC …, 2016 - pubs.rsc.org
Muscle atrophy often occurs in cachexia of various inflammation-related diseases. Systemic
inflammation and the inflammatory pathway contribute to cachexia-induced muscle atrophy …

BST204, a Rg3 and Rh2 enriched ginseng extract, upregulates myotube formation and mitochondrial function in TNF-α-induced atrophic myotubes

SJ Lee, M Im, SK Park, JY Kim, EY So… - The American Journal …, 2020 - World Scientific
The loss of skeletal muscle mass and function is a serious consequence of chronic diseases
and aging. BST204 is a purified ginseng (the root of Panax ginseng) extract that has been …

Carnosol ameliorated cancer cachexia-associated myotube atrophy by targeting P5CS and its downstream pathways

QY Fang, YP Wang, RQ Zhang, M Fan… - Frontiers in …, 2024 - frontiersin.org
Introduction: Carnosol exhibited ameliorating effects on muscle atrophy of mice developed
cancer cachexia in our previous research. Method: Here, the ameliorating effects of carnosol …

[HTML][HTML] Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy

L Zhiyin, C Jinliang, C Qiunan, Y Yunfei… - Biomedicine & …, 2021 - Elsevier
Muscle atrophy and weakness are the adverse effects of long-term or high dose usage of
glucocorticoids. In the present study, we explored the effects of fucoxanthin (10 μM) on …

Skeletal muscle atrophy was alleviated by salidroside through suppressing oxidative stress and inflammation during denervation

Z Huang, Q Fang, W Ma, Q Zhang, J Qiu… - Frontiers in …, 2019 - frontiersin.org
Skeletal muscle atrophy is a common and debilitating condition that lacks an effective
therapy. Oxidative stress and inflammation are two main molecular mechanisms involved in …

Pyropia yezoensis protein protects against TNF‑α‑induced myotube atrophy in C2C12 myotubes via the NF‑κB signaling pathway

MK Lee, YH Choi, TJ Nam - Molecular Medicine …, 2021 - spandidos-publications.com
The protein extracted from red algae Pyropia yezoensis has various biological activities,
including anti‑inflammatory, anticancer, antioxidant, and antiobesity properties. However …

Ginsenoside Rg3 upregulates myotube formation and mitochondrial function, thereby protecting myotube atrophy induced by tumor necrosis factor-alpha

SJ Lee, JH Bae, H Lee, H Lee, J Park, JS Kang… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Ginsenoside Rg3 from Panax ginseng has
reported to have multiple pharmacological activities including anti-diabetics, anti …