[HTML][HTML] Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches

IA Savin, MA Zenkova, AV Sen'kova - International Journal of Molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

Molecular mechanisms of pulmonary fibrosis and current treatment

K Kuwano, N Hagimoto, N Hara - Current molecular medicine, 2001 - ingentaconnect.com
Pulmonary fibrosis is a common response to various insults or injuries to the lung. Although
there are various initiating factors or causes, the terminal stages are characterized by …

Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis

M Gharaee-Kermani, SH Phan - Current pharmaceutical design, 2005 - ingentaconnect.com
Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair,
resulting in the replacement of normal functional tissue with an abnormal accumulation of …

Pulmonary fibrosis: from pathogenesis to clinical decision-making

T Koudstaal, M Funke-Chambour, M Kreuter… - Trends in molecular …, 2023 - cell.com
Pulmonary fibrosis (PF) encompasses a spectrum of chronic lung diseases that
progressively impact the interstitium, resulting in compromised gas exchange …

[HTML][HTML] Molecular biomarkers in idiopathic pulmonary fibrosis: state of the art and future directions

A Stainer, P Faverio, S Busnelli, M Catalano… - International Journal of …, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF), the most lethal form of interstitial pneumonia of unknown
cause, is associated with a specific radiological and histopathological pattern (the so-called …

Integrating mechanisms of pulmonary fibrosis

TA Wynn - Journal of Experimental Medicine, 2011 - rupress.org
Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …

Tissue remodelling in pulmonary fibrosis

L Knudsen, C Ruppert, M Ochs - Cell and Tissue Research, 2017 - Springer
Many lung diseases result in fibrotic remodelling. Fibrotic lung disorders can be divided into
diseases with known and unknown aetiology. Among those with unknown aetiology …

[HTML][HTML] Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis

THG Phan, P Paliogiannis, GK Nasrallah… - Cellular and Molecular …, 2021 - Springer
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …

The pathogenesis of pulmonary fibrosis: a moving target

WA Wuyts, C Agostini, KM Antoniou… - European …, 2013 - Eur Respiratory Soc
Pulmonary fibrosis is the end stage of many diffuse parenchymal lung diseases. It is
characterised by excessive matrix formation leading to destruction of the normal lung …

Novel therapeutic approaches for pulmonary fibrosis

A Datta, CJ Scotton… - British journal of …, 2011 - Wiley Online Library
Pulmonary fibrosis represents the end stage of a number of heterogeneous conditions and
is, to a greater or lesser degree, the hallmark of the interstitial lung diseases. It is …