Background Cardiac troponin (cTn) and N-terminal pro-B-type natriuretic peptide (NT-
proBNP) are increasingly used clinically to evaluate and prognosticate acute myocardial …

Background Cardiac biomarkers have increasing application in pediatric populations,
including congenital heart disease, myocarditis, and heart failure. Clinical practice is limited …

This study aimed to provide reliable pediatric reference values for N-terminal pro-brain
natriuretic peptide (NT-proBNP) and high-sensitive Troponin T (hsTnT) obtained from a …

BACKGROUND: Brain natriuretic peptide (BNP) and N-terminal pro-brain natriuretic peptide
(NT-proBNP) have been shown to be useful biomarkers for the diagnosis of heart failure …

Background: Myocardial injury is an important pediatric diagnosis. Establishing normative
data from a representative pediatric sample is vital to provide accurate upper reference limits …

Apparently healthy children often complain of chest pain, especially after physical exercise.
Cardiac biomarker levels are often measured, but the clinical relevance of these assays in …

Over the past 10 years cardiac troponin (cTn) immunoassays have been improved in
analytical sensitivity and precision thereby allowing the measurement of cTn in adult healthy …

International societies and expert groups recommend using sex-specific upper reference
limits (URLs) 1 for interpretation of high-sensitivity cardiac troponin (hs-cTnI/T) assays (1, 2) …

BACKGROUND Reference intervals of high-sensitivity troponin T (hs-cTnT) and N-terminal
pro-B–type natriuretic peptide (NT-proBNP) have been determined from Western …

BACKGROUND There is little information available on cardiac troponin concentrations in
healthy young children. METHODS Using a precommercial high-sensitivity assay from …