[HTML][HTML] SARS-CoV-2 vaccine induced atypical immune responses in antibody defects: everybody does their best

AF Salinas, EP Mortari, S Terreri, C Quintarelli… - Journal of clinical …, 2021 - Springer
Background Data on immune responses to SARS-CoV-2 in patients with Primary Antibody
Deficiencies (PAD) are limited to infected patients and to heterogeneous cohorts after …

[HTML][HTML] B cell response induced by SARS-CoV-2 infection is boosted by the BNT162b2 vaccine in primary antibody deficiencies

F Pulvirenti, A Fernandez Salinas, C Milito, S Terreri… - Cells, 2021 - mdpi.com
Background: Patients with primary antibody deficiencies are at risk in the current COVID-19
pandemic due to their impaired response to infection and vaccination. Specifically, patients …

[HTML][HTML] SARS-CoV-2 vaccine responses in individuals with antibody deficiency: findings from the COV-AD study

AM Shields, SE Faustini, HJ Hill, S Al-Taei… - Journal of clinical …, 2022 - Springer
Background Vaccination prevents severe morbidity and mortality from COVID-19 in the
general population. The immunogenicity and efficacy of SARS-CoV-2 vaccines in patients …

[HTML][HTML] Robust antibody and T cell responses to SARS-CoV-2 in patients with antibody deficiency

H Kinoshita, J Durkee-Shock… - Journal of Clinical …, 2021 - Springer
Immunocompromised patients, including those with inborn errors of immunity (IEI), may be at
increased risk for severe or prolonged infections with SARS-CoV-2 (Zhu et al. N Engl J Med …

[HTML][HTML] T-cell defects associated to lack of spike-specific antibodies after BNT162b2 full immunization followed by a booster dose in patients with common variable …

F Pulvirenti, S Di Cecca, M Sinibaldi, E Piano Mortari… - Cells, 2022 - mdpi.com
Following the third booster dose of the mRNA vaccine, Common Variable Immune
Deficiencies (CVID) patients may not produce specific antibodies against the virus spike …

[HTML][HTML] SARS-CoV-2 T cell response in severe and fatal COVID-19 in primary antibody deficiency patients without specific humoral immunity

S Steiner, T Schwarz, VM Corman, L Gebert… - Frontiers in …, 2022 - frontiersin.org
Morbidity and mortality of COVID-19 is increased in patients with inborn errors of immunity
(IEI). Age and comorbidities and also impaired type I interferon immunity were identified as …

[HTML][HTML] Antigen-Specific CD4+ T-Cell Activation in Primary Antibody Deficiency After BNT162b2 mRNA COVID-19 Vaccination

KMT Sauerwein, CB Geier, RF Stemberger… - Frontiers in …, 2022 - frontiersin.org
Previous studies on immune responses following COVID-19 vaccination in patients with
common variable immunodeficiency (CVID) were inconclusive with respect to the ability of …

[HTML][HTML] The immune response to SARS-CoV-2 vaccination: insights learned from adult patients with common variable immune deficiency

I Quinti, F Locatelli, R Carsetti - Frontiers in Immunology, 2022 - frontiersin.org
CVID patients have an increased susceptibility to vaccine-preventable infections. The
question on the potential benefits of immunization of CVID patients against SARS-CoV-2 …

[HTML][HTML] Immunogenicity of the mRNA-1273 COVID-19 vaccine in adult patients with inborn errors of immunity

LPM van Leeuwen, CH GeurtsvanKessel… - Journal of Allergy and …, 2022 - Elsevier
Background Patients with inborn errors of immunity (IEI) are at increased risk of severe
coronavirus disease-2019 (COVID-19). Effective vaccination against COVID-19 is therefore …

[HTML][HTML] Elevated CD21low B Cell Frequency Is a Marker of Poor Immunity to Pfizer-BioNTech BNT162b2 mRNA Vaccine Against SARS-CoV-2 in Patients with …

P Bergman, D Wullimann, Y Gao… - Journal of Clinical …, 2022 - Springer
Purpose Limited data is available on the effect of COVID-19 vaccination in
immunocompromised individuals. Here, we provide the results from vaccinating a single …