Interactions between long non‑coding RNAs and RNA‑binding proteins in cancer

H Huang, L Li, K Wen - Oncology reports, 2021 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) fulfill important roles in the majority of cellular processes.
Previous studies have demonstrated that lncRNAs are involved in the pathogenesis of …

RNA-binding proteins as important regulators of long non-coding RNAs in cancer

K Jonas, GA Calin, M Pichler - International journal of molecular sciences, 2020 - mdpi.com
The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …

[HTML][HTML] Long non-coding RNA and RNA-binding protein interactions in cancer: experimental and machine learning approaches

H Shaath, R Vishnubalaji, R Elango… - Seminars in cancer …, 2022 - Elsevier
Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …

New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

The characteristic landscape of lncRNAs classified by RBP–lncRNA interactions across 10 cancers

Q Zhang, Y Wei, Z Yan, C Wu, Z Chang, Y Zhu… - Molecular …, 2017 - pubs.rsc.org
RNA-binding proteins (RBPs) are key regulators of gene expression. Some long non-coding
RNAs (lncRNAs) affect gene expression by interacting with RBPs. However, whether this …

Multidimensional crosstalk between RNA-binding proteins and noncoding RNAs in cancer biology

L Li, H Miao, Y Chang, H Yao, Y Zhao, F Wu… - Seminars in cancer …, 2021 - Elsevier
RNA-binding proteins (RBPs) are well-known to bind RNA via a set of RNA-binding domains
(RBDs) and determine the fate and function of their RNA targets; inversely, some RBPs, in …

Gene expression regulations by long noncoding RNAs and their roles in cancer

X Du, H Wei, G Qu, Z Tian, W Yao, Q Cai - Pathology-Research and …, 2020 - Elsevier
Cancers are deadly diseases. The general mystery of carcinogenesis, primary and acquired
drug resistance and distant organ metastasis are still puzzles to be solved. Long noncoding …

LncRNA-mediated regulation of cell signaling in cancer

WX Peng, P Koirala, YY Mo - Oncogene, 2017 - nature.com
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …

Methods to study long noncoding RNA biology in cancer

ML Luo - The Long and Short Non-coding RNAs in Cancer …, 2016 - Springer
Thousands of long noncoding RNAs (lncRNAs) have been discovered in recent years. The
functions of lncRNAs range broadly from regulating chromatin structure and gene …

A mechanistic view of long noncoding RNAs in cancer

L Winkler, N Dimitrova - Wiley Interdisciplinary Reviews: RNA, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) have emerged as important modulators of a wide range of
biological processes in normal and disease states. In particular, lncRNAs have garnered …