Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

DNA is increasingly being used as the engineering material of choice for the construction of
nanoscale circuits, structures, and motors. Many of these enzyme-free constructions function …

Toehold-mediated strand displacement is the most abundantly used method to achieve
dynamic switching in DNA-based nanotechnology. An “invader” strand binds to the “toehold” …

The specificity and predictability of Watson–Crick base pairing make DNA a powerful and
versatile material for engineering at the nanoscale. This has enabled the construction of a …

DNA has many unique properties beyond encoding genetic information, one of which is its
physicochemical stability based on Watson–Crick base pairing. Differences in sequence …

Single-nucleotide variants (SNVs) that are strongly associated with many genetic diseases
and tumors are important both biologically and clinically. Detection of SNVs holds great …

Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for
controlling reaction kinetics. Although the dependence of strand displacement kinetics on …

Strand displacement cascades are commonly used to make dynamically assembled
structures. Particularly, the concept of “toehold-mediated DNA branch migration reactions” …

Colocalization can strongly alter the kinetics and efficiency of chemical processes. For
instance, in DNA-templated synthesis unfavorable reactions are sped up by placing …

Conspectus The base sequence in DNA dictates structural and reactivity features of the
biopolymer. These properties are implemented to use DNA as a unique material for …